Testosterone

cytochrome P450 family 17 subfamily A member 1 ; Homo sapiens







43 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34655046 Aberrant H19 Expression Disrupts Ovarian Cyp17 and Testosterone Production and Is Associated with Polycystic Ovary Syndrome in Women. 2022 Apr 2
2 33436964 Gene expression and functional abnormalities in XX/Sry Leydig cells. 2021 Jan 12 1
3 34333840 Warning against second-generation antiandrogen for metastatic castration sensitive prostate cancer. 2021 Nov 1
4 32712140 Polymorphisms in androgen metabolism genes with serum testosterone levels and prognosis in androgen-deprivation therapy. 2020 Nov 1
5 29438723 Discovery and development of ODM-204: A Novel nonsteroidal compound for the treatment of castration-resistant prostate cancer by blocking the androgen receptor and inhibiting CYP17A1. 2019 Sep 1
6 29438521 Leydig cell dysfunction is associated with post-transcriptional deregulation of CYP17A1 in men with Sertoli cell-only syndrome. 2018 Apr 1 2
7 29951171 A Study on the Clinical Outcome of Abiraterone Acetate in Castration Resistant Prostate Cancer Patients. 2018 Jan 1 1
8 28179152 The six most widely used selective serotonin reuptake inhibitors decrease androgens and increase estrogens in the H295R cell line. 2017 Jun 1
9 28978327 Abiraterone acetate plus LHRH therapy versus abiraterone acetate while sparing LHRH therapy in patients with progressive, metastatic and chemotherapy-naïve, castration-resistant prostate cancer (SPARE): study protocol for a randomized controlled trial. 2017 Oct 4 2
10 26626779 Effects of Nandrolone Stimulation on Testosterone Biosynthesis in Leydig Cells. 2016 Jun 1
11 25208301 Association of CYP17A1 gene -34T/C polymorphism with polycystic ovary syndrome in Han Chinese population. 2015 Jan 1
12 25929975 The CYP17 MspA1 Polymorphism and the Gender Dysphoria. 2015 Jun 1
13 26150586 Strategies to Circumvent Testosterone Surge and Disease Flare in Advanced Prostate Cancer: Emerging Treatment Paradigms. 2015 Jul 2
14 26770559 Genetic polymorphisms in the androgen metabolism pathway and risk of prostate cancer in low incidence Malaysian ethnic groups. 2015 2
15 24140493 The polymorphism (-600 C>A) of CpG methylation site at the promoter region of CYP17A1 and its association of male infertility and testosterone levels. 2014 Jan 15 1
16 25153259 Molecular adaptations of testosterone-producing Leydig cells during systemic in vivo blockade of the androgen receptor. 2014 Oct 1
17 25629114 Re: the polymorphism (-600 C>A) of CpG methylation site at the promoter region of CYP17A1 and its association of male infertility and testosterone levels. 2014 Jul 1
18 23337755 Agents that target androgen synthesis in castration-resistant prostate cancer. 2013 Jan-Feb 1
19 23628604 SET/PP2A system regulates androgen production in ovarian follicles in vitro. 2013 Jul 15 2
20 24223995 Endurance exercise and conjugated linoleic acid (CLA) supplementation up-regulate CYP17A1 and stimulate testosterone biosynthesis. 2013 2
21 22123334 Abiraterone acetate in castration-resistant prostate cancer. 2012 Mar 1
22 22174412 Direct regulation of androgen receptor activity by potent CYP17 inhibitors in prostate cancer cells. 2012 Feb 3 1
23 22184395 Effects of abiraterone acetate on androgen signaling in castrate-resistant prostate cancer in bone. 2012 Feb 20 1
24 22198164 Abiraterone acetate: redefining hormone treatment for advanced prostate cancer. 2012 Mar 1
25 22430753 [Abiraterone acetate: a novel therapeutic option in hormone-refractory prostate cancer]. 2012 Feb 1
26 22451619 Abiraterone in prostate cancer: a new angle to an old problem. 2012 Apr 1 2
27 22752297 Effect of abiraterone acetate plus prednisone on the QT interval in patients with metastatic castration-resistant prostate cancer. 2012 Aug 1
28 21511288 Hypospadias risk and polymorphism in SRD5A2 and CYP17 genes: case-control study among Indian children. 2011 Jun 1
29 21676446 Polymorphisms in the P450 c17 (17-hydroxylase/17, 20-Lyase) gene: association with estradiol and testosterone concentration in hypospadias. 2011 Oct 1
30 21948762 Association of serum sex steroid levels and bone mineral density with CYP17 and CYP19 gene polymorphisms in postmenopausal women in Turkey. 2011 Sep 9 1
31 21985170 Abiraterone acetate: in metastatic castration-resistant prostate cancer. 2011 Oct 22 1
32 17326004 Sexual hormones in human skin. 2007 Feb 1
33 16103457 Identifying susceptibility genes for prostate cancer--a family-based association study of polymorphisms in CYP17, CYP19, CYP11A1, and LH-beta. 2005 Aug 1
34 14560315 Comprehensive evaluation of the association between prostate cancer and genotypes/haplotypes in CYP17A1, CYP3A4, and SRD5A2. 2004 Apr 1
35 15477877 Serum sex steroid hormone levels and polymorphisms of CYP17 and SRD5A2: implication for prostate cancer risk. 2004 2
36 12915666 The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway. 2003 Aug 1
37 14522586 5alpha-reduced C21 steroids are substrates for human cytochrome P450c17. 2003 Oct 15 1
38 11895872 A polymorphism in the CYP17 gene and risk of prostate cancer. 2002 Mar 2
39 11303586 The association between polymorphisms in the CYP17 and 5alpha-reductase (SRD5A2) genes and serum androgen concentrations in men. 2001 Mar 1
40 11341336 A common promotor variant in the cytochrome P450c17alpha (CYP17) gene is associated with bioavailability testosterone levels and bone size in men. 2001 May 2
41 9858495 Development and differentiation of the interstitial and tubular compartments of fetal porcine testes. 1999 Jan 2
42 9794458 Regulation of 3beta-hydroxysteroid dehydrogenase in gonadotropin-induced steroidogenic desensitization of Leydig cells. 1998 Nov 1
43 9863627 Time-course effects of human recombinant luteinizing hormone on porcine Leydig cell specific differentiated functions. 1998 Sep 25 1