Pub. Date : 2013 Jul 15
PMID : 23628604
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The central role of PP2A in SET-mediated regulation of testosterone production was confirmed by the finding that SET promoted the lyase activity of P450c17 and that PP2A inhibited its lyase activity. | Testosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 2 | Taken together, these results reveal a specific, SET-initiated, PP2A-mediated, pathway that leads to the increased lyase activity of P450c17 and testosterone biosynthesis. | Testosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |