Title : Molecular adaptations of testosterone-producing Leydig cells during systemic in vivo blockade of the androgen receptor.

Pub. Date : 2014 Oct

PMID : 25153259






1 Functional Relationships(s)
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1 Testosterone-reduced expression of some steroidogenic enzymes/proteins (Tspo,StAR,Hsd3b1/2) and transcription factors (Nur77,Gata4,Dax1) was completely abrogated, while decreased expression of Star,Cyp11a1,Cyp17a1,Hsd17b4,Creb1a was partially prevented. Testosterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens