Pub. Date : 2018 Apr 1
PMID : 29438521
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | STUDY QUESTION: Is the expression of steroidogenic enzyme 17alpha-Hydroxylase/17,20-Lyase (CYP17A1) down-regulated in Leydig cells (LCs) of men with spermatogenic failure and compensated impairment of LC function, i.e. a low testosterone to LH (T/LH) ratio? | Testosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 2 | CYP17A1 is a key enzyme in the testosterone pathway and has been implicated in the steroidogenic lesion produced by E2 stimulation. | Testosterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |