| 1 |
35287432 | Importance of Asparagine 202 in Manipulating Active Site Structure and Substrate Preference for Human CYP17A1. | 2022 Apr 5 |
1 |
| 2 |
35366770 | Insights into Interactions of Human Cytochrome P450 17A1: Review. | 2022 Apr 1 |
2 |
| 3 |
34662099 | Mechanism of the Clinically Relevant E305G Mutation in Human P450 CYP17A1. | 2021 Nov 2 |
1 |
| 4 |
31369102 | Adrenal adaptation in potassium-depleted men: role of progesterone? | 2020 Nov 1 |
1 |
| 5 |
32215889 | Clinical, Molecular, Functional, and Structural Characterization of CYP17A1 Mutations in Brazilian Patients with 17-Hydroxylase Deficiency. | 2020 Mar |
1 |
| 6 |
31509771 | Effect of mutations in porcine CYB5A and CYP17A1 on the metabolism of pregnenolone. | 2019 Dec |
2 |
| 7 |
29710837 | Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency. | 2018 Apr 29 |
1 |
| 8 |
30229581 | Functional Identification of Compound Heterozygous Mutations in the CYP17A1 Gene Resulting in Combined 17α-Hydroxylase/17,20-Lyase Deficiency. | 2018 Sep |
1 |
| 9 |
28387522 | Mechanism of Cytochrome P450 17A1-Catalyzed Hydroxylase and Lyase Reactions. | 2017 May 22 |
3 |
| 10 |
26668369 | Unveiling the crucial intermediates in androgen production. | 2015 Dec 29 |
2 |
| 11 |
24671419 | Human cytochrome P450 17A1 conformational selection: modulation by ligand and cytochrome b5. | 2014 May 16 |
2 |
| 12 |
23620596 | Substrate-modulated cytochrome P450 17A1 and cytochrome b5 interactions revealed by NMR. | 2013 Jun 7 |
2 |
| 13 |
22951291 | The activities of 5α-reductase and 17,20-lyase determine the direction through androgen synthesis pathways in patients with 21-hydroxylase deficiency. | 2012 Nov |
1 |
| 14 |
21586563 | High-yield expression of a catalytically active membrane-bound protein: human P450 oxidoreductase. | 2011 Jul |
1 |
| 15 |
16595705 | Direct electrochemistry of human, bovine and porcine cytochrome P450c17. | 2006 Apr |
1 |
| 16 |
16103714 | Disorders of androgen synthesis--from cholesterol to dehydroepiandrosterone. | 2005 |
1 |
| 17 |
12464253 | Ovine steroid 17alpha-hydroxylase cytochrome P450: characteristics of the hydroxylase and lyase activities of the adrenal cortex enzyme. | 2003 Jan 1 |
1 |
| 18 |
12631293 | Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor. Role of recombinant cytochrome b5 and P450 reductase. | 2003 Mar |
1 |
| 19 |
14504283 | CYP17 mutation E305G causes isolated 17,20-lyase deficiency by selectively altering substrate binding. | 2003 Dec 5 |
1 |
| 20 |
11867265 | Assessment of the ability of type 2 cytochrome b5 to modulate 17,20-lyase activity of human P450c17. | 2002 Jan |
1 |
| 21 |
12423360 | Baboon cytochrome P450 17alpha-hydroxylase/17,20-lyase (CYP17). | 2002 Nov |
1 |
| 22 |
12573809 | Androgen biosynthesis from cholesterol to DHEA. | 2002 Dec 30 |
1 |
| 23 |
9888582 | The molecular basis of isolated 17,20 lyase deficiency. | 1998 Aug-Nov |
2 |
| 24 |
9890062 | Early steps in androgen biosynthesis: from cholesterol to DHEA. | 1998 Apr |
1 |
| 25 |
8396144 | Expression and purification of functional human 17 alpha-hydroxylase/17,20-lyase (P450c17) in Escherichia coli. Use of this system for study of a novel form of combined 17 alpha-hydroxylase/17,20-lyase deficiency. | 1993 Sep 15 |
4 |