| 1 |
35451580 | miR-205 Reverses MDR-1 Mediated Doxorubicin Resistance via PTEN in Human Liver Cancer HepG2 Cells. | 2022 Mar |
6 |
| 2 |
33675923 | The APEX1/miRNA-27a-5p axis plays key roles in progression, metastasis and targeted chemotherapy of gastric cancer. | 2021 Apr 15 |
1 |
| 3 |
33752173 | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression. | 2021 Mar 22 |
1 |
| 4 |
34190523 | Co-administration of apigenin with doxorubicin enhances anti-migration and antiproliferative effects via PI3K/PTEN/AKT pathway in prostate cancer cells. | 2021 Jun |
1 |
| 5 |
34357784 | Retraction of: miR-155 Affects Osteosarcoma MG-63 Cell Autophagy Induced by Adriamycin Through Regulating PTEN-I3K/AKT/mTOR Signaling Pathway (doi: 10.1089/cbr.2017.2306). | 2021 Sep |
1 |
| 6 |
34695518 | Fisetin-induced PTEN expression reverses cellular senescence by inhibiting the mTORC2-Akt Ser473 phosphorylation pathway in vascular smooth muscle cells. | 2021 Dec |
1 |
| 7 |
31899608 | MicroRNA-221 promotes breast cancer resistance to adriamycin via modulation of PTEN/Akt/mTOR signaling. | 2020 Feb |
2 |
| 8 |
32016465 | Low‑intensity ultrasound enhances the antitumor effects of doxorubicin on hepatocellular carcinoma cells through the ROS‑miR‑21‑PTEN axis. | 2020 Mar |
2 |
| 9 |
32133289 | Combination of Ruthenium Complex and Doxorubicin Synergistically Inhibits Cancer Cell Growth by Down-Regulating PI3K/AKT Signaling Pathway. | 2020 |
1 |
| 10 |
32184626 | Berberine Reverses Doxorubicin Resistance by Inhibiting Autophagy Through the PTEN/Akt/mTOR Signaling Pathway in Breast Cancer. | 2020 |
1 |
| 11 |
30945389 | Combination of tanshinone IIA and doxorubicin possesses synergism and attenuation effects on doxorubicin in the treatment of breast cancer. | 2019 Jun |
1 |
| 12 |
30983514 | MiR-202-5p/PTEN mediates doxorubicin-resistance of breast cancer cells via PI3K/Akt signaling pathway. | 2019 |
3 |
| 13 |
31087712 | Overexpression of tensin homolog deleted on chromosome ten (PTEN) by ciglitazone sensitizes doxorubicin-resistance leukemia cancer cells to treatment. | 2019 Sep |
2 |
| 14 |
29393355 | miR‑21‑5p confers doxorubicin resistance in gastric cancer cells by targeting PTEN and TIMP3. | 2018 Apr |
1 |
| 15 |
29412697 | miR-155 Affects Osteosarcoma MG-63 Cell Autophagy Induced by Adriamycin Through Regulating PTEN-PI3K/AKT/mTOR Signaling Pathway. | 2018 Feb |
2 |
| 16 |
29968951 | MicroRNA-760 Inhibits Doxorubicin Resistance in Hepatocellular Carcinoma through Regulating Notch1/Hes1-PTEN/Akt Signaling Pathway. | 2018 Aug |
2 |
| 17 |
30095997 | PTEN inhibitor VO-OHpic attenuates inflammatory M1 macrophages and cardiac remodeling in doxorubicin-induced cardiomyopathy. | 2018 Nov 1 |
3 |
| 18 |
30344742 | Doxorubicin resistance induces IL6 activation in the colon cancer cell line LS180. | 2018 Nov |
2 |
| 19 |
27746366 | MiR-222 promotes drug-resistance of breast cancer cells to adriamycin via modulation of PTEN/Akt/FOXO1 pathway. | 2017 Jan 5 |
1 |
| 20 |
28126034 | Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer. | 2017 Jan 26 |
3 |
| 21 |
28464252 | Long Noncoding RNA lncARSR Promotes Doxorubicin Resistance in Hepatocellular Carcinoma via Modulating PTEN-PI3K/Akt Pathway. | 2017 Dec |
3 |
| 22 |
28684738 | Mechanistic clues to the protective effect of chrysin against doxorubicin-induced cardiomyopathy: Plausible roles of p53, MAPK and AKT pathways. | 2017 Jul 6 |
1 |
| 23 |
26905328 | Phosphatase and Tensin Homolog Is a Potential Target for Ovarian Cancer Sensitization to Cytotoxic Agents. | 2016 May |
1 |
| 24 |
27095949 | Hypoxia-induced modulation of PTEN activity and EMT phenotypes in lung cancers. | 2016 |
1 |
| 25 |
27523474 | MicroRNA-29a contributes to drug-resistance of breast cancer cells to adriamycin through PTEN/AKT/GSK3β signaling pathway. | 2016 Nov 15 |
1 |
| 26 |
27699665 | miR-222 induces Adriamycin resistance in breast cancer through PTEN/Akt/p27kip1 pathway. | 2016 Nov |
1 |
| 27 |
25612678 | Quercetin Increase the Chemosensitivity of Breast Cancer Cells to Doxorubicin Via PTEN/Akt Pathway. | 2015 |
5 |
| 28 |
25661377 | Aldo-keto reductase 1C3 (AKR1C3) is associated with the doxorubicin resistance in human breast cancer via PTEN loss. | 2015 Feb |
3 |
| 29 |
26745097 | Combined Treatment with 2-Deoxy-D-Glucose and Doxorubicin Enhances the in Vitro Efficiency of Breast Cancer Radiotherapy. | 2015 |
1 |
| 30 |
24675890 | Doxorubicin enhances Snail/LSD1-mediated PTEN suppression in a PARP1-dependent manner. | 2014 |
2 |
| 31 |
23546450 | miRNA-200c increases the sensitivity of breast cancer cells to doxorubicin through the suppression of E-cadherin-mediated PTEN/Akt signaling. | 2013 May |
1 |
| 32 |
23843848 | Enhancing the Effects of Low Dose Doxorubicin Treatment by the Radiation in T47D and SKBR3 Breast Cancer Cells. | 2013 Jun |
3 |
| 33 |
22185283 | Effect of phosphatase and tensin homology deleted on chromosome 10 (PTEN) gene transfection on reversal of multidrug resistance in K562/ADM cells. | 2012 Jul |
1 |
| 34 |
22781804 | [Experimental study of up-regulating PTEN gene on increasing the chemosensitivity in K562/ADM cells]. | 2012 May |
1 |
| 35 |
21040738 | Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells. | 2011 Jan 10 |
1 |
| 36 |
21820606 | MicroRNA-21 modulates chemosensitivity of breast cancer cells to doxorubicin by targeting PTEN. | 2011 May |
1 |
| 37 |
20646419 | [The expression and role of PTEN in doxorubicin induced gastric cancer cell apoptosis]. | 2010 May |
5 |
| 38 |
19843859 | Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells. | 2009 Nov 1 |
1 |
| 39 |
17935137 | Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death. | 2008 Jan 15 |
2 |
| 40 |
18256541 | Akt inactivates ERK causing decreased response to chemotherapeutic drugs in advanced CaP cells. | 2008 Mar 1 |
2 |
| 41 |
18332865 | Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors. | 2008 Jul 3 |
4 |
| 42 |
18702307 | [Role of PTEN protein in multidrug resistance of prostate cancer cells]. | 2008 May-Jun |
2 |
| 43 |
17330857 | Histone deacetylase inhibitor trichostatin a potentiates doxorubicin-induced apoptosis by up-regulating PTEN expression. | 2007 Apr 15 |
6 |
| 44 |
17359293 | PTEN augments doxorubicin-induced apoptosis in PTEN-null Ishikawa cells. | 2007 Jul-Aug |
8 |
| 45 |
16854453 | Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance. | 2006 |
2 |
| 46 |
15829377 | PTEN gene therapy induces growth inhibition and increases efficacy of chemotherapy in prostate cancer. | 2005 |
1 |
| 47 |
16264263 | PTEN/MMAC1 enhances the growth inhibition by anticancer drugs with downregulation of IGF-II expression in gastric cancer cells. | 2005 Oct 31 |
1 |
| 48 |
16438844 | [Sensitivity of PTEN gene-transfected endometrial carcinoma cell line to doxorubicin-induced apoptosis]. | 2005 Sep |
8 |
| 49 |
15548710 | Phosphatidylinositol 3'-kinase activation leads to multidrug resistance protein-1 expression and subsequent chemoresistance in advanced prostate cancer cells. | 2004 Nov 15 |
1 |
| 50 |
12923562 | In vivo gene therapy of human bladder cancer with PTEN suppresses tumor growth, downregulates phosphorylated Akt, and increases sensitivity to doxorubicin. | 2003 Sep |
1 |