Title : Combination of tanshinone IIA and doxorubicin possesses synergism and attenuation effects on doxorubicin in the treatment of breast cancer.

Pub. Date : 2019 Jun

PMID : 30945389






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Our in vitro studies showed that Tan IIA could enhance the sensitivity of breast cancer cells to Dox through inhibiting the PTEN/AKT pathway and downregulating the expression of efflux ABC transporters including P-gp, BCRP, and MRP1. Doxorubicin phosphatase and tensin homolog Homo sapiens