Pub. Date : 2013 Jun
PMID : 23843848
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | METHODS: We have studied the effect of 1, 1.5, and 2 Gy doses of 9 MV X-rays along with 1 microM doxorubicin on inducing cell death, apoptosis and also p53 and PTEN gene expression in T47D and SKBR3 breast cancer cells. | Doxorubicin | phosphatase and tensin homolog | Homo sapiens |
2 | RESULTS: Doxorubicin treatment resulted in upregulation of radiation-induced levels of p53 and downregulation of PTEN at 1 and 1.5 Gy in T47D breast cancer cells, as well as downregulation of p53 mRNA level of expression and upregulation of PTEN mRNA level of expression in SKBR3 breast cancer cell line. | Doxorubicin | phosphatase and tensin homolog | Homo sapiens |
3 | RESULTS: Doxorubicin treatment resulted in upregulation of radiation-induced levels of p53 and downregulation of PTEN at 1 and 1.5 Gy in T47D breast cancer cells, as well as downregulation of p53 mRNA level of expression and upregulation of PTEN mRNA level of expression in SKBR3 breast cancer cell line. | Doxorubicin | phosphatase and tensin homolog | Homo sapiens |