Pub. Date : 2020 Feb
PMID : 31899608
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MicroRNA-221 promotes breast cancer resistance to adriamycin via modulation of PTEN/Akt/mTOR signaling. | Doxorubicin | phosphatase and tensin homolog | Homo sapiens |
| 2 | Taken together, these findings suggest microRNA-221 suppresses PTEN transcription and activates Akt/mTOR pathway, which in turn enhances breast cancer resistance to adriamycin and promotes cancer development. | Doxorubicin | phosphatase and tensin homolog | Homo sapiens |