Docetaxel

ATP binding cassette subfamily B member 1 ; Homo sapiens







123 Article(s)
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1 34928144 Discovery and Characterization of Potent Dual P-Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations. 2022 Jan 13 3
2 34988655 Association between gene polymorphism and adverse effects in cancer patients receiving docetaxel treatment: a meta-analysis. 2022 Feb 2
3 35533911 An ester derivative of tenacigenin B from Marsdenia tenacissima (Roxb.) Wight et Arn reversed paclitaxel-induced MDR in vitro and in vivo by inhibiting both P-gp and MRP2. 2022 Aug 10 1
4 33125673 Association of plasma docetaxel levels with ABCB1 gene polymorphisms and tumour response in locally advanced breast cancer patients of South India on neo-adjuvant chemotherapy. 2021 Mar 6
5 33464545 Effect of Food on the Pharmacokinetics of the Oral Docetaxel Tablet Formulation ModraDoc006 Combined with Ritonavir (ModraDoc006/r) in Patients with Advanced Solid Tumours. 2021 Mar 1
6 33499040 Advances in Nanocarriers for Effective Delivery of Docetaxel in the Treatment of Lung Cancer: An Overview. 2021 Jan 22 2
7 33536797 Pharmacokinetics and Toxicities of Oral Docetaxel Formulations Co-Administered with Ritonavir in Phase I Trials. 2021 1
8 33649517 Investigating the influence of relevant pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of orally administered docetaxel combined with ritonavir. 2021 Jun 1
9 33658706 Cystine supplementation rebalances the redox homeostasis of microenvironment in non-small cell lung cancer cells and reverses their resistance to docetaxel. 2021 Dec 2
10 33709626 ModraDoc006, an oral docetaxel formulation in combination with ritonavir (ModraDoc006/r), in metastatic castration-resistant prostate cancer patients: A phase Ib study. 2021 Aug 1
11 33799432 Molecular Profiling of Docetaxel-Resistant Prostate Cancer Cells Identifies Multiple Mechanisms of Therapeutic Resistance. 2021 Mar 14 1
12 34268580 Differences in P-glycoprotein activity in human and rodent blood-brain barrier assessed by mechanistic modelling. 2021 Sep 2
13 34326198 Activation of the ABCB1 Amplicon in Docetaxel- and Cabazitaxel-Resistant Prostate Cancer Cells. 2021 Oct 1
14 34439209 Circulating Cell-Free DNA as Biomarker of Taxane Resistance in Metastatic Castration-Resistant Prostate Cancer. 2021 Aug 12 2
15 32134535 Docetaxel-resistant prostate cancer cells become sensitive to gemcitabine due to the upregulation of ABCB1. 2020 May 3
16 32581798 Maslinic Acid Enhances Docetaxel Response in Human Docetaxel-Resistant Triple Negative Breast Carcinoma MDA-MB-231 Cells via Regulating MELK-FoxM1-ABCB1 Signaling Cascade. 2020 2
17 32748110 ABCB1 and ABCC2 genetic polymorphism as risk factors for neutropenia in esophageal cancer patients treated with docetaxel, cisplatin, and 5-fluorouracil chemotherapy. 2020 Aug 1
18 32756886 Association Between ABCB1 Genetic Variants and Persistent Chemotherapy-Induced Alopecia in Women With Breast Cancer. 2020 Sep 1 1
19 30637776 Influence of ABCB1 C3435T and C1236T gene polymorphisms on tumour response to docetaxel-based neo-adjuvant chemotherapy in locally advanced breast cancer patients of South India. 2019 Apr 2
20 30638237 Formulating a single thioether-bridged oleate prodrug into a self-nanoemulsifying drug delivery system to facilitate oral absorption of docetaxel. 2019 Feb 26 5
21 30814489 Over-expression of FSIP1 promotes breast cancer progression and confers resistance to docetaxel via MRP1 stabilization. 2019 Feb 27 1
22 31090467 Co-encapsulation of docetaxel and cyclosporin A into SNEDDS to promote oral cancer chemotherapy. 2019 Dec 4
23 31350703 Involvement of the MDR1 gene and glycolipids in anticancer drug-resistance of human ovarian carcinoma-derived cells. 2019 Oct 2
24 31638462 The ABCB1 3435C > T polymorphism influences docetaxel transportation in ovarian cancer. 2019 Oct 1
25 29132176 Verapamil (VER) Enhances the Cytotoxic Effects of Docetaxel and Vinblastine Combined Therapy Against Non-Small Cell Lung Cancer Cell Lines. 2018 Mar 1
26 29679509 Pharmacokinetic properties of wogonin and its herb-drug interactions with docetaxel in rats with mammary tumors. 2018 Apr 21 2
27 29885788 Association of Allelic Interaction of Single Nucleotide Polymorphisms of Influx and Efflux Transporters Genes With Nonhematologic Adverse Events of Docetaxel in Breast Cancer Patients. 2018 Oct 1
28 30148955 Co-delivery of Docetaxel and Disulfonate Tetraphenyl Chlorin in One Nanoparticle Produces Strong Synergism between Chemo- and Photodynamic Therapy in Drug-Sensitive and -Resistant Cancer Cells. 2018 Oct 1 1
29 30453546 Androgen Receptor Splice Variant 7 Drives the Growth of Castration Resistant Prostate Cancer without Being Involved in the Efficacy of Taxane Chemotherapy. 2018 Nov 16 4
30 30555232 Activation of polymeric nanoparticle intracellular targeting overcomes chemodrug resistance in human primary patient breast cancer cells. 2018 2
31 30555629 The estrogen receptor variants β2 and β5 induce stem cell characteristics and chemotherapy resistance in prostate cancer through activation of hypoxic signaling. 2018 Nov 20 1
32 28104912 Paclitaxel-resistant cancer cell-derived secretomes elicit ABCB1-associated docetaxel cross-resistance and escape from apoptosis through FOXO3a-driven glycolytic regulation. 2017 Jan 20 2
33 28698198 ABCB1 Mediates Cabazitaxel-Docetaxel Cross-Resistance in Advanced Prostate Cancer. 2017 Oct 2
34 28787019 Sensitivity of docetaxel-resistant MCF-7 breast cancer cells to microtubule-destabilizing agents including vinca alkaloids and colchicine-site binding agents. 2017 2
35 28938627 Prostate Tumor Overexpressed-1 (PTOV1) promotes docetaxel-resistance and survival of castration resistant prostate cancer cells. 2017 Aug 29 1
36 28959367 Elacridar, a third-generation ABCB1 inhibitor, overcomes resistance to docetaxel in non-small cell lung cancer. 2017 Oct 9
37 29714413 [Expression of AXL enhances docetaxel-resistance of prostate cancer cells]. 2017 Apr 1
38 26548759 Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma. 2016 1
39 26764117 Evaluation of TPGS-modified thermo-sensitive Pluronic PF127 hydrogel as a potential carrier to reverse the resistance of P-gp-overexpressing SMMC-7721 cell lines. 2016 Apr 1 2
40 26882453 Efficacy of tamoxifen in combination with docetaxel in patients with advanced non-small-cell lung cancer pretreated with platinum-based chemotherapy. 2016 Jun 3
41 27114800 Co-treatment by docetaxel and vinblastine breaks down P-glycoprotein mediated chemo-resistance. 2016 Mar 2
42 27284014 Multiplicity of acquired cross-resistance in paclitaxel-resistant cancer cells is associated with feedback control of TUBB3 via FOXO3a-mediated ABCB1 regulation. 2016 Jun 7 1
43 27574448 Polymorphism of CYP3A4 and ABCB1 genes increase the risk of neuropathy in breast cancer patients treated with paclitaxel and docetaxel. 2016 1
44 27629782 Roles of aldo-keto reductases 1B10 and 1C3 and ATP-binding cassette transporter in docetaxel tolerance. 2016 Dec 3
45 27727250 Notch-1 Confers Chemoresistance in Lung Adenocarcinoma to Taxanes through AP-1/microRNA-451 Mediated Regulation of MDR-1. 2016 Oct 11 2
46 27941276 ABCB1 Is Upregulated in Acquisition of Taxane Resistance: Lessons from Esophageal Squamous Cell Carcinoma Cell Lines. 2016 Dec 1
47 28642838 Adaptive pathways and emerging strategies overcoming treatment resistance in castration resistant prostate cancer. 2016 Oct 1
48 24888374 EGFR mediates docetaxel resistance in human castration-resistant prostate cancer through the Akt-dependent expression of ABCB1 (MDR1). 2015 Apr 3
49 25410489 ABCB1 polymorphism as prognostic factor in breast cancer patients treated with docetaxel and doxorubicin neoadjuvant chemotherapy. 2015 Jan 2
50 25596703 Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways. 2015 Jun 1