Title : Activation of polymeric nanoparticle intracellular targeting overcomes chemodrug resistance in human primary patient breast cancer cells.

Pub. Date : 2018

PMID : 30555232






2 Functional Relationships(s)
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1 In addition, PLGA NPs, especially FA incorporated, limited DTX efflux by reducing expression of ABCG2 (3.2-fold) and MDR1 (2.86-fold), which were highly activated by free DTX. Docetaxel ATP binding cassette subfamily B member 1 Homo sapiens
2 In addition, PLGA NPs, especially FA incorporated, limited DTX efflux by reducing expression of ABCG2 (3.2-fold) and MDR1 (2.86-fold), which were highly activated by free DTX. Docetaxel ATP binding cassette subfamily B member 1 Homo sapiens