| 1 |
34498807 | Evaluation of the potential drug interactions mediated through P-gp, OCT2, and MATE1/2K with filgotinib in healthy subjects. | 2022 Feb |
1 |
| 2 |
34668334 | Physiologically-based pharmacokinetic modeling to evaluate in vitro-to-in vivo extrapolation for intestinal P-glycoprotein inhibition. | 2022 Jan |
5 |
| 3 |
35247290 | A Phase 1, Open-Label Study to Evaluate the Effect of Food and Concomitant Itraconazole Administration on the Pharmacokinetics of AMG 986 in Healthy Subjects. | 2022 Mar 5 |
2 |
| 4 |
33387374 | Urinary Excretion of Nadolol as a Possible In Vivo Probe for Drug Interactions Involving P-Glycoprotein. | 2021 Jun |
3 |
| 5 |
34260894 | Reduced physiologically-based pharmacokinetic model of dabigatran etexilate-dabigatran and its application for prediction of intestinal P-gp-mediated drug-drug interactions. | 2021 Oct 1 |
1 |
| 6 |
32459872 | Pharmacokinetic Drug Interactions of an Orally Available TRH Analog (Rovatirelin) With a CYP3A4/5 and P-Glycoprotein Inhibitor (Itraconazole). | 2020 Oct |
4 |
| 7 |
29635947 | An update on the clinical pharmacokinetics of fexofenadine enantiomers. | 2018 Apr |
1 |
| 8 |
30166405 | Relationship between In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Systemic Tacrolimus Metabolite/Parent Drug Ratio in Renal Transplant Recipients and Healthy Volunteers. | 2018 Nov |
1 |
| 9 |
30171694 | CYP3A but not P-gp plays a relevant role in the in vivo intestinal and hepatic clearance of the delta-specific phosphoinositide-3 kinase inhibitor leniolisib. | 2018 Sep |
1 |
| 10 |
25670260 | Itraconazole therapy in a pancreatic adenocarcinoma patient: A case report. | 2016 Jun |
1 |
| 11 |
26467209 | Prediction of area under the curve for a p-glycoprotein, a CYP3A4 and a CYP2C9 substrate using a single time point strategy: assessment using fexofenadine, itraconazole and losartan and metabolites. | 2016 |
1 |
| 12 |
27001813 | Inhibitory Potential of Antifungal Drugs on ATP-Binding Cassette Transporters P-Glycoprotein, MRP1 to MRP5, BCRP, and BSEP. | 2016 Jun |
1 |
| 13 |
25907295 | Itraconazole and clarithromycin inhibit P-glycoprotein activity in primary human sinonasal epithelial cells. | 2015 Jun |
4 |
| 14 |
26124377 | Combination Chemotherapy with Itraconazole for Treating Metastatic Pancreatic Cancer in the Second-line or Additional Setting. | 2015 Jul |
1 |
| 15 |
26184414 | Effect of CYP3A5 and ABCB1 polymorphisms on the interaction between tacrolimus and itraconazole in patients with connective tissue disease. | 2015 Sep |
3 |
| 16 |
24212378 | In vitro predictability of drug-drug interaction likelihood of P-glycoprotein-mediated efflux of dabigatran etexilate based on [I]2/IC50 threshold. | 2014 Feb |
2 |
| 17 |
24386966 | Development of optimized supersaturable self-nanoemulsifying systems of ezetimibe: effect of polymers and efflux transporters. | 2014 Apr |
1 |
| 18 |
23099620 | Ticlopidine inhibits both O-demethylation and renal clearance of tramadol, increasing the exposure to it, but itraconazole has no marked effect on the ticlopidine-tramadol interaction. | 2013 Apr |
1 |
| 19 |
21420575 | [Drug interactions in critically-ill patients. An important factor in the use of micafungin?]. | 2011 Mar |
1 |
| 20 |
21484807 | Substrate- and species-dependent inhibition of P-glycoprotein-mediated transport: implications for predicting in vivo drug interactions. | 2011 Aug |
1 |
| 21 |
21771587 | Drug interaction of (S)-warfarin, and not (R)-warfarin, with itraconazole in a hematopoietic stem cell transplant recipient. | 2011 Oct 9 |
1 |
| 22 |
19947891 | Clinical pharmacokinetics of fexofenadine enantiomers. | 2010 Jan |
2 |
| 23 |
19309762 | Bioanalytical methods for the determination of itraconazole and hydroxyitraconazole: overview from clinical pharmacology, pharmacokinetic, pharmacodynamic and metabolism perspectives. | 2009 Jul |
3 |
| 24 |
18294330 | The different effects of itraconazole on the pharmacokinetics of fexofenadine enantiomers. | 2008 May |
5 |
| 25 |
19025521 | Itraconazole, a potent inhibitor of P-glycoprotein, moderately increases plasma concentrations of oral morphine. | 2008 Nov |
3 |
| 26 |
17304149 | Effect of itraconazole on pharmacokinetics of paroxetine: the role of gut transporters. | 2007 Feb |
2 |
| 27 |
15969931 | Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs. | 2005 Jun |
1 |
| 28 |
15286096 | Renal interaction between itraconazole and cimetidine. | 2004 Aug |
3 |
| 29 |
12709722 | Effect of itraconazole on the pharmacokinetics of rosuvastatin. | 2003 Apr |
1 |
| 30 |
11751127 | Interaction of common azole antifungals with P glycoprotein. | 2002 Jan |
2 |
| 31 |
11808341 | [Molecular mechanisms on drug transporters in the drug absorption and disposition]. | 2002 Jan |
1 |
| 32 |
12237270 | P-glycoprotein as the mediator of itraconazole-digoxin interaction. | 2002 Sep |
1 |