Title : Substrate- and species-dependent inhibition of P-glycoprotein-mediated transport: implications for predicting in vivo drug interactions.

Pub. Date : 2011 Aug

PMID : 21484807






1 Functional Relationships(s)
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1 The inhibition of P-gp-mediated efflux of these two fluorescent substrates by several drugs, including quinidine and itraconazole, was found to be substrate- and/or species-dependent. Itraconazole ATP binding cassette subfamily B member 1 Homo sapiens