Sepharose

coagulation factor II, thrombin ; Homo sapiens







102 Article(s)
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1 24369620 [Preparation of thrombin affinity chromatography media]. 2013 Aug 2
2 21707870 Approach to the treatment, characterization and diagnosis of an acquired auto-antibody directed against factors prothrombin, factor X and factor IX: a case report and review of the literature. 2012 Jan 1
3 22025420 Measurement of fibrin concentration by fast field-cycling NMR. 2012 May 1
4 18279654 A method for the prevention of thrombin-induced degradation of recombinant proteins. 2008 Apr 15 2
5 16431918 Role of Hirudin-like factor Va heavy chain sequences in prothrombinase function. 2006 Mar 31 1
6 12591924 Deletion of P1 arginine in a novel antithrombin variant (antithrombin London) abolishes inhibitory activity but enhances heparin affinity and is associated with early onset thrombosis. 2003 Apr 18 1
7 12788947 Structural requirements for expression of factor Va activity. 2003 Aug 29 1
8 12935804 Manufacturing process of anti-thrombin III concentrate: viral safety validation studies and effect of column re-use on viral clearance. 2003 Sep 1
9 11171108 Preparation of anhydrothrombin and characterization of its interaction with natural thrombin substrates. 2001 Mar 1 1
10 11327827 Activation of prostate-specific antigen precursor (pro-PSA) by prostin, a novel human prostatic serine protease identified by degenerate PCR. 2001 Feb 13 1
11 10956019 A novel venombin B from agkistrodon contortrix contortrix: evidence for recognition properties in the surface around the primary specificity pocket different from thrombin. 2000 Aug 22 1
12 10541273 Prothrombin gene expression in rat kidneys provides an opportunity to examine its role in urinary stone pathogenesis. 1999 Nov 2
13 9494024 Thrombin binds to soluble fibrin degradation products where it is protected from inhibition by heparin-antithrombin but susceptible to inactivation by antithrombin-independent inhibitors. 1998 Feb 17 1
14 9634038 Gene expression of prothrombin in the human kidney and its potential relevance to kidney stone disease. 1998 May 1
15 9848182 [Chromatography of thrombin and antithrombin III on biospecific silochromes]. 1998 May-Jun 1
16 9136969 Identification of a monoclonal thrombin inhibitor associated with multiple myeloma and a severe bleeding disorder. 1997 Apr 1
17 9325262 Evidence for allosteric linkage between exosites 1 and 2 of thrombin. 1997 Oct 10 1
18 8605204 A model for human cytochrome P450 2D6 based on homology modeling and NMR studies of substrate binding. 1996 Apr 9 1
19 8672510 Iterative optimization of high-affinity protease inhibitors using phage display. 2. Plasma kallikrein and thrombin. 1996 Jun 18 1
20 8812854 Immobilized hirudin and hirudin-based peptides used for the purification of recombinant human thrombin prepared from recombinant human prothrombin. 1996 Sep 2
21 8883269 Effect of heparin on the activation of factor XI by fibrin-bound thrombin. 1996 Sep 3
22 7547035 Stable expression in Chinese hamster ovary cells of a homogeneous recombinant active fragment of human platelet glycoprotein Ib alpha. 1995 1
23 7858951 Sequence-independent detection of gene family homologs: identification of a transcript encoding a molluscan serine protease homologous to the pancreatic enzymes of vertebrates. 1995 Jan 1
24 8040268 Platelet factor 4 modulates the mitogenic activity of basic fibroblast growth factor. 1994 Jul 1
25 8136018 Interaction of thrombin with antithrombin, heparin cofactor II, and protein C inhibitor. 1993 Dec 2
26 8376410 Expression and characterization of functionally active fragments of the platelet glycoprotein (GP) Ib-IX complex in mammalian cells. Incorporation of GP Ib alpha into the cell surface membrane. 1993 Sep 25 1
27 8429008 Inhibition of dysthrombins Quick I and II by heparin cofactor II and antithrombin. 1993 Feb 15 1
28 8470887 Hydrophobic affinity chromatography of human thrombin. 1993 Apr 2
29 1320300 Partial characterization of an autoantibody recognizing the secondary binding site(s) of thrombin in a patient with recurrent spontaneous arterial thrombosis. 1992 Feb 3 1
30 1377216 Neutralization of the anticoagulant effects of glycosaminoglycans by serum amyloid P component: comparison with other plasma and platelet proteins. 1992 Jul 1
31 1412220 Affinity chromatography of platelets on immobilized thrombin: retention of catalytic activity by platelet-bound thrombin. 1992 Aug 15 1
32 1412223 Non-specific influence of chemical modification upon the properties of antithrombin III:modification of carboxyl groups. 1992 Aug 15 1
33 1601896 Molecular recognition sites on factor Xa which participate in the prothrombinase complex. 1992 Jun 15 1
34 1894195 Effect of hirudin on the chemotactic properties of alpha-thrombin. 1991 1
35 1911389 Antithrombin Glasgow II: alanine 382 to threonine mutation in the serpin P12 position, resulting in a substrate reaction with thrombin. 1991 Sep 2
36 1998601 Antithrombin Vicenza, Ala 384 to Pro (GCA to CCA) mutation, transforming the inhibitor into a substrate. 1991 Jan 1
37 2029579 Antithrombin-III-Hamilton, Ala 382 to Thr: an antithrombin-III variant that acts as a substrate but not an inhibitor of alpha-thrombin and factor Xa. 1991 May 15 2
38 2053103 A synthetic analog of fibrinogen alpha 27-50 is an inhibitor of thrombin. 1991 Feb 12 1
39 2264022 Coagulation impact on chemotactic activity generation for polymorphonuclear leukocytes. 1990 Sep 15 1
40 2354150 Human alpha- to zeta-thrombin cleavage occurs with neutrophil cathepsin G or chymotrypsin while fibrinogen clotting activity is retained. 1990 Apr 10 3
41 2465100 Increased immunoreactivity of plasma after fibrinolytic activation in an anti-DD ELISA system. Role of soluble crosslinked fibrin polymers. 1989 Mar 1
42 2722864 A novel amino acid substitution in the reactive site of a congenital variant antithrombin. Antithrombin pescara, ARG393 to pro, caused by a CGT to CCT mutation. 1989 Jun 15 1
43 2781509 Antithrombin Chicago, amino acid substitution of arginine 393 to histidine. 1989 Jun 15 2
44 2458152 Conformational states of vitronectin: preferential expression of an antigenic epitope when vitronectin is covalently and noncovalently complexed with thrombin-antithrombin III or treated with urea. 1988 Sep 1
45 2853710 Functionally active thrombomodulin is present in human platelets. 1988 Oct 1
46 3075905 Purification and characterization of a prothrombin activator from the venom of the Australian brown snake, Pseudonaja textilis textilis. 1988 Nov 1
47 3188251 [Affinity chromatography of human gamma-thrombin on fibrin-agarose]. 1988 Jul-Aug 2
48 3191114 Antithrombin III Utah: proline-407 to leucine mutation in a highly conserved region near the inhibitor reactive site. 1988 Aug 9 1
49 3280421 Purification of plasma protein. 1988 1
50 3378041 Localization of the binding site on fibrin for the secondary binding site of thrombin. 1988 Mar 22 2