Title : Non-specific influence of chemical modification upon the properties of antithrombin III:modification of carboxyl groups.

Pub. Date : 1992 Aug 15

PMID : 1412223






1 Functional Relationships(s)
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1 The modified antithrombin III retained a reduced affinity for heparin (eluting at 0.3M NaCl from heparin Agarose) and was observed to be a competitive inhibitor of the heparin-dependent rate of inhibition of thrombin by native antithrombin III. Sepharose coagulation factor II, thrombin Homo sapiens