Dexmedetomidine

tumor necrosis factor ; Mus musculus







37 Article(s)
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1 34625874 Effects of Dexmedetomidine and Oxycodone on Neurocognitive and Inflammatory Response After Tourniquet-Induced Ischemia-Reperfusion Injury. 2022 Feb 1
2 35412062 Dexmedetomidine attenuates hippocampal neuroinflammation in postoperative neurocognitive disorders by inhibiting microRNA-329-3p and activating the CREB1/IL1RA axis. 2022 Jul 1
3 35502244 Dexmedetomidine Activates Akt, STAT6 and IRF4 Modulating Cytoprotection and Macrophage Anti-Inflammatory Phenotype Against Acute Lung Injury in vivo and in vitro. 2022 1
4 35538293 MiR-665 Participates in the Protective Effect of Dexmedetomidine in Ischemic Stroke by ROCK2/NF-κB Axis. 2022 Jul 1
5 33179100 Dexmedetomidine attenuates sevoflurane‑induced neurocognitive impairment through α2‑adrenoceptors. 2021 Jan 1
6 33220278 Dexmedetomidine inhibits LPS-induced inflammatory responses through peroxisome proliferator-activated receptor gamma (PPARγ) activation following binding to α2 adrenoceptors. 2021 Feb 5 2
7 33821300 Dexmedetomidine ameliorates lipopolysaccharide-induced acute lung injury by inhibiting the PI3K/Akt/FoxO1 signaling pathway. 2021 Jun 2
8 34172807 Modulation of microglial phenotypes by dexmedetomidine through TREM2 reduces neuroinflammation in heatstroke. 2021 Jun 25 1
9 34278508 Dexmedetomidine alleviates early brain injury following traumatic brain injury by inhibiting autophagy and neuroinflammation through the ROS/Nrf2 signaling pathway. 2021 Sep 2
10 34421084 Dexmedetomidine relieved neuropathic pain and inflammation response induced by CCI through HMGB1/TLR4/NF-κB signal pathway. 2021 Aug 20 1
11 34451922 Sedative and Immunosuppressive Effects of Dexmedetomidine in Transplantation. 2021 Aug 22 1
12 34692497 Immunomodulatory Effects of Perioperative Dexmedetomidine in Ovarian Cancer: An In Vitro and Xenograft Mouse Model Study. 2021 1
13 34747306 Protective effect of dexmedetomidine in cecal ligation perforation-induced acute lung injury through HMGB1/RAGE pathway regulation and pyroptosis activation. 2021 Dec 1
14 31823113 Dexmedetomidine Inhibits Neuroinflammation by Altering Microglial M1/M2 Polarization Through MAPK/ERK Pathway. 2020 Feb 3
15 31954762 Dexmedetomidine attenuates ethanol-induced inhibition of hippocampal neurogenesis in neonatal mice. 2020 Mar 1 1
16 32145512 Dexmedetomidine preconditioning alleviated murine liver ischemia and reperfusion injury by promoting macrophage M2 activation via PPARγ/STAT3 signaling. 2020 Mar 4 1
17 31030092 Dexmedetomidine alleviated lipopolysaccharide/D-galactosamine-induced acute liver injury in mice. 2019 Jul 1
18 31185237 Protective effect of dexmedetomidine against diabetic hyperglycemia-exacerbated cerebral ischemia/reperfusion injury: An in vivo and in vitro study. 2019 Oct 15 1
19 31682847 The therapeutic effect of dexmedetomidine on protection from renal failure via inhibiting KDM5A in lipopolysaccharide-induced sepsis of mice. 2019 Dec 15 1
20 29269298 Dexmedetomidine attenuates pancreatic injury and inflammatory response in mice with pancreatitis by possible reduction of NLRP3 activation and up-regulation of NET expression. 2018 Jan 22 1
21 29351316 Dexmedetomidine reduces lipopolysaccharide induced neuroinflammation, sickness behavior, and anhedonia. 2018 1
22 29545877 3-Methyladenine and dexmedetomidine reverse lipopolysaccharide-induced acute lung injury through the inhibition of inflammation and autophagy. 2018 Apr 1
23 30071186 The effect of dexmedetomidine on inflammatory inhibition and microglial polarization in BV-2 cells. 2018 Oct 1
24 28173746 Neurodegenerative changes and neuroapoptosis induced by systemic lipopolysaccharide administration are reversed by dexmedetomidine treatment in mice. 2017 Apr 1
25 28224201 Dexmedetomidine protects against cisplatin-induced acute kidney injury in mice through regulating apoptosis and inflammation. 2017 May 1
26 28247333 Dexmedetomidine Regulates 6-hydroxydopamine-Induced Microglial Polarization. 2017 May 1
27 28555511 Mitigation of inflammation using the intravenous anesthetic dexmedetomidine in the mouse air pouch model. 2017 Aug 1
28 28784305 Dexmedetomidine (DEX) protects against hepatic ischemia/reperfusion (I/R) injury by suppressing inflammation and oxidative stress in NLRC5 deficient mice. 2017 Nov 18 2
29 26911944 [Role of α7 nicotinic acetylcholine receptor in attenuation of endotoxin induced delirium with dexmedetomidine in mice]. 2016 Feb 2
30 28139820 Protective role of dexmedetomidine in unmethylated CpG-induced inflammation responses in BV2 microglia cells. 2016 2
31 26211495 Dexmedetomidine attenuates acute lung injury induced by lipopolysaccharide in mouse through inhibition of MAPK pathway. 2015 Oct 1
32 26702389 The role of spleen in the treatment of experimental lipopolysaccharide-induced sepsis with dexmedetomidine. 2015 1
33 23850057 Interruption of spinal cord microglial signaling by alpha-2 agonist dexmedetomidine in a murine model of delayed paraplegia. 2014 Apr 1
34 24445644 Locally injected dexmedetomidine inhibits carrageenin-induced inflammatory responses in the injected region. 2014 Feb 1
35 24803295 Dexmedetomidine controls systemic cytokine levels through the cholinergic anti-inflammatory pathway. 2014 Oct 1
36 23463181 Effects of dexmedetomidine on early and late cytokines during polymicrobial sepsis in mice. 2013 May 3
37 22092133 Dexmedetomidine attenuates remote lung injury induced by renal ischemia-reperfusion in mice. 2011 Nov 1