Title : Modulation of microglial phenotypes by dexmedetomidine through TREM2 reduces neuroinflammation in heatstroke.

Pub. Date : 2021 Jun 25

PMID : 34172807






1 Functional Relationships(s)
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1 We found that DEX treatment reduced the expression of CD68, iNOS, TNF-alpha, and IL-1beta, and increased the expression of CD206, Arg1, IL-10 and TGF-beta in microglia, ameliorating heatstroke induced neuroinflammation and brain injury in mice. Dexmedetomidine tumor necrosis factor Mus musculus