Title : Dexmedetomidine reduces lipopolysaccharide induced neuroinflammation, sickness behavior, and anhedonia.

Pub. Date : 2018

PMID : 29351316






1 Functional Relationships(s)
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1 The mRNA expression of TNF-alpha, MCP-1, indoleamine 2, 3 dioxygenase (IDO), caspase-3, and iNOS were increased in the brain of LPS-challenged mice, which were reduced by Dex but not vehicle. Dexmedetomidine tumor necrosis factor Mus musculus