| 1 |
33486190 | Functional analysis of isoflavones using patient-derived human colonic organoids. | 2021 Jan 20 |
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32276266 | Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways. | 2020 Apr 10 |
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| 3 |
31611933 | Inhibitory effects of genistein in combination with gefitinib on the hepatocellular carcinoma Hep3B cell line. | 2019 Nov |
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| 4 |
29693152 | Genistein reduces the activation of AKT and EGFR, and the production of IL6 in cholangiocarcinoma cells involving estrogen and estrogen receptors. | 2018 Jul |
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| 5 |
27861885 | Sensitivity of TP53-Mutated Cancer Cells to the Phytoestrogen Genistein Is Associated With Direct Inhibition of Plk1 Activity. | 2017 Oct |
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| 6 |
28240227 | Nonsteroidal anti-inflammatory drugs modulate cellular glycosaminoglycan synthesis by affecting EGFR and PI3K signaling pathways. | 2017 Feb 27 |
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| 7 |
28255863 | Genistein inhibited ammonia induced astrocyte swelling by inhibiting NF-κB activation-mediated nitric oxide formation. | 2017 Jun |
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| 8 |
24631489 | Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation. | 2014 May |
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| 9 |
24699889 | Genistein increases glycosaminoglycan levels in mucopolysaccharidosis type I cell models. | 2014 Sep |
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| 10 |
25401399 | Synthetic genistein glycosides inhibiting EGFR phosphorylation enhance the effect of radiation in HCT 116 colon cancer cells. | 2014 Nov 13 |
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| 11 |
22293631 | A phase 2 cancer chemoprevention biomarker trial of isoflavone G-2535 (genistein) in presurgical bladder cancer patients. | 2012 Apr |
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| 12 |
21603581 | Genistein increases epidermal growth factor receptor signaling and promotes tumor progression in advanced human prostate cancer. | 2011 |
2 |
| 13 |
20138837 | Lipid raft cholesterol and genistein inhibit the cell viability of prostate cancer cells via the partial contribution of EGFR-Akt/p70S6k pathway and down-regulation of androgen receptor. | 2010 Mar 5 |
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| 14 |
19288574 | Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines. | 2009 May 15 |
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| 15 |
19347870 | Down-regulation of epidermal growth factor receptor induced by estrogens and phytoestrogens promotes the differentiation of U2OS human osteosarcoma cells. | 2009 Jul |
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| 16 |
18424208 | Developmental changes and the impact of isoflavones on mRNA expression of IGF-I receptor, EGF receptor and related growth factors in porcine skeletal muscle cell cultures. | 2008 Oct |
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| 17 |
19149197 | [Molecular docking of epidermal growth factor receptor tyramine kinase domain and its inhibitor genistein]. | 2008 Oct |
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| 18 |
17234721 | Soy phytochemicals synergistically enhance the preventive effect of tamoxifen on the growth of estrogen-dependent human breast carcinoma in mice. | 2007 Jun |
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| 19 |
17295235 | Genistein sensitizes inhibitory effect of tamoxifen on the growth of estrogen receptor-positive and HER2-overexpressing human breast cancer cells. | 2007 Jul |
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| 20 |
17934341 | Signaling pathway for 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced TNF-alpha production in differentiated THP-1 human macrophages. | 2007 Aug 31 |
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| 21 |
16470170 | Retinoid-induced epidermal hyperplasia is mediated by epidermal growth factor receptor activation via specific induction of its ligands heparin-binding EGF and amphiregulin in human skin in vivo. | 2006 Apr |
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| 22 |
16197614 | Molecular effects of the isoflavonoid genistein in prostate cancer. | 2005 Sep |
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| 23 |
15634453 | [The effects of genistein on epidermal growth factor receptor mediated signal transduction pathway in human ovarian carcinoma cells lines SKOV3 and its xenograft in nude mice]. | 2004 Dec |
3 |
| 24 |
12709393 | Signaling and distribution of NPR-Bi, the human splice form of the natriuretic peptide receptor type B. | 2003 Aug |
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| 25 |
11170137 | Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells. | 2001 Feb 1 |
2 |
| 26 |
11348889 | Critical role of Rho-kinase and MEK/ERK pathways for angiotensin II-induced plasminogen activator inhibitor type-1 gene expression. | 2001 May |
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| 27 |
10982794 | Stimulation of the mitogen-activated protein kinase cascade and tyrosine phosphorylation of the epidermal growth factor receptor by hepatopoietin. | 2000 Dec 1 |
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| 28 |
11007941 | Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents. | 2000 Oct 15 |
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| 29 |
10090785 | Use of a pharmacophore model for the design of EGFR tyrosine kinase inhibitors: isoflavones and 3-phenyl-4(1H)-quinolones. | 1999 Mar 25 |
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| 30 |
10226546 | Enhancement of chemosensitivity and programmed cell death by tyrosine kinase inhibitors correlates with EGFR expression in non-small cell lung cancer cells. | 1999 Jan-Feb |
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| 31 |
10381396 | 4-hydroxynonenal triggers an epidermal growth factor receptor-linked signal pathway for growth inhibition. | 1999 Jul |
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| 32 |
9588219 | EGF-dependent and independent programmed cell death pathways in NCI-H596 nonsmall cell lung cancer cells. | 1998 Apr 28 |
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| 33 |
9607569 | In vivo toxicity, pharmacokinetics, and anticancer activity of Genistein linked to recombinant human epidermal growth factor. | 1998 May |
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| 34 |
9833772 | Inhibition of human bladder cancer cell motility by genistein is dependent on epidermal growth factor receptor but not p21ras gene expression. | 1998 Dec 9 |
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| 35 |
9848510 | Mechanisms of action of the soy isoflavone genistein: emerging role for its effects via transforming growth factor beta signaling pathways. | 1998 Dec |
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| 36 |
9060993 | Inhibition of tyrosine kinase activity decreases expression of surfactant protein A in a human lung adenocarcinoma cell line independent of epidermal growth factor receptor. | 1997 Mar 1 |
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| 37 |
9309250 | Genistein analogues: effects on epidermal growth factor receptor tyrosine kinase and on stress-activated pathways. | 1997 |
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| 38 |
8702388 | Genistein, a tyrosine kinase inhibitor, reduces EGF-induced EGF receptor internalization and degradation in human hepatoma HepG2 cells. | 1996 Jul 16 |
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| 39 |
7884565 | Evaluation of the biochemical targets of genistein in tumor cells. | 1995 Mar |
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| 40 |
8297123 | Antiproliferative effect of tyrosine kinase inhibitors in epidermal growth factor-stimulated growth of human gastric cancer cells. | 1993 Nov-Dec |
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| 41 |
3106339 | Genistein, a specific inhibitor of tyrosine-specific protein kinases. | 1987 Apr 25 |
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