Title : A phase 2 cancer chemoprevention biomarker trial of isoflavone G-2535 (genistein) in presurgical bladder cancer patients.

Pub. Date : 2012 Apr

PMID : 22293631






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The soy compound genistein has been observed preclinically to inhibit bladder cancer growth with one potential mechanism being the inhibition of epidermal growth factor receptor phosphorylation (p-EGFR). Genistein epidermal growth factor receptor Homo sapiens
2 Genistein displayed a possible bimodal effect (more effective at the lower dose) on bladder cancer tissue EGFR phosphorylation that should be evaluated further, possibly in combination with other agents. Genistein epidermal growth factor receptor Homo sapiens