Pub. Date : 1995 Mar
PMID : 7884565
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Genistein is a potent in vitro inhibitor of protein tyrosine kinase (PTK) activity, especially that of the epidermal growth factor receptor (EGF-R), having little effect on serine/threonine kinases. | Genistein | epidermal growth factor receptor | Homo sapiens |
| 2 | Genistein is a potent in vitro inhibitor of protein tyrosine kinase (PTK) activity, especially that of the epidermal growth factor receptor (EGF-R), having little effect on serine/threonine kinases. | Genistein | epidermal growth factor receptor | Homo sapiens |
| 3 | This led to the suggestion that genistein might exert its anti-cancer effects through inhibiting the activity of EGF-R PTK, or other crucial PTK"s in vivo. | Genistein | epidermal growth factor receptor | Homo sapiens |
| 4 | Subsequent studies on intact tumor cell lines demonstrated that EGF-R and other growth factor receptors are able to transmit mitogenic signals in the presence of genistein. | Genistein | epidermal growth factor receptor | Homo sapiens |