Title : A pivotal role for HOXB7 protein in endocrine resistant breast cancer.

Pub. Date : 2015

PMID : 26697525






1 Functional Relationships(s)
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Protein Name
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1 EGFR expression is upregulated by direct binding of HOXB7 to the EGFR promoter, while HOXB7 functions as a cofactor with ERalpha to cause overexpression of multiple ER-target genes, including HER2, in tamoxifen resistant breast cancer cells. Tamoxifen epidermal growth factor receptor Homo sapiens