Guanosine Triphosphate

Rac family small GTPase 1 ; Mus musculus







76 Article(s)
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1 35326399 Vav1 Promotes B-Cell Lymphoma Development. 2022 Mar 10 1
2 32460619 TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTORC1 axis. 2021 Jun 1
3 33809389 A Novel Vasoactive Peptide "PG1" from Buffalo Ice-Cream Protects from Angiotensin-Evoked High Blood Pressure. 2021 Mar 12 1
4 32112978 Inhibitory effects of ceramide kinase on Rac1 activation, lamellipodium formation, cell migration, and metastasis of A549 lung cancer cells. 2020 Jun 1
5 32277014 Vav1 and mutant K-Ras synergize in the early development of pancreatic ductal adenocarcinoma in mice. 2020 May 1
6 30159893 NKCC1 promotes EMT-like process in GBM via RhoA and Rac1 signaling pathways. 2019 Feb 1
7 30748033 The trafficking protein JFC1 regulates Rac1-GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migration. 2019 Jun 5
8 31321300 HACE1 deficiency leads to structural and functional neurodevelopmental defects. 2019 Jun 1
9 31483951 Eucalyptol Ameliorates Dysfunction of Actin Cytoskeleton Formation and Focal Adhesion Assembly in Glucose-Loaded Podocytes and Diabetic Kidney. 2019 Nov 1
10 31484924 Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions. 2019 Sep 4 4
11 29422652 RAGE-aptamer attenuates deoxycorticosterone acetate/salt-induced renal injury in mice. 2018 Feb 8 1
12 29481523 Flavonoids extracted from leaves of Diospyros kaki regulates RhoA activity to rescue synapse loss and reverse memory impairment in APP/PS1 mice. 2018 May 2 2
13 30350139 RhoG-ELMO1-RAC1 is involved in phagocytosis suppressed by mono-butyl phthalate in TM4 cells. 2018 Dec 1
14 27028843 Cannabinoid Receptor 1 Mediates Homing of Bone Marrow-Derived Mesenchymal Stem Cells Triggered by Chronic Liver Injury. 2017 Jan 2
15 28947541 Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria. 2017 Nov 1 2
16 26939003 Deletion of Rac1GTPase in the Myeloid Lineage Protects against Inflammation-Mediated Kidney Injury in Mice. 2016 1
17 27632208 Sevoflurane Inhalation Accelerates the Long-Term Memory Consolidation via Small GTPase Overexpression in the Hippocampus of Mice in Adolescence. 2016 1
18 25289457 Redox regulation of Rac1 by thiol oxidation. 2015 Feb 4
19 25578041 Pan-PI-3 kinase inhibitor SF1126 shows antitumor and antiangiogenic activity in renal cell carcinoma. 2015 Mar 1
20 25958207 Targeting the isoprenoid pathway to abrogate progression of pulmonary fibrosis. 2015 Sep 1
21 26116550 The cytohesin guanosine exchange factors (GEFs) are required to promote HGF-mediated renal recovery after acute kidney injury (AKI) in mice. 2015 Jun 2
22 24297853 The small GTPase Rac1 is required for smooth muscle contraction. 2014 Mar 1 1
23 24561795 A link between the nuclear-localized srGAP3 and the SWI/SNF chromatin remodeler Brg1. 2014 May 1
24 24628852 Expression and activity of Rac1 is negatively affected in the dehydroepiandrosterone induced polycystic ovary of mouse. 2014 Mar 14 1
25 25099735 Kcnj10 is a major type of K+ channel in mouse corneal epithelial cells and plays a role in initiating EGFR signaling. 2014 Oct 15 2
26 25331951 Src homology 2 domain containing protein 5 (SH2D5) binds the breakpoint cluster region protein, BCR, and regulates levels of Rac1-GTP. 2014 Dec 19 4
27 25365944 Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma. 2014 Nov 30 3
28 25378391 Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis. 2014 Dec 26 1
29 23355623 Vascular endothelial adrenomedullin-RAMP2 system is essential for vascular integrity and organ homeostasis. 2013 Feb 19 1
30 23921306 Role of small GTPase protein Rac1 in cardiovascular diseases: development of new selective pharmacological inhibitors. 2013 Nov 1
31 24231357 Inhibition of the TRPC5 ion channel protects the kidney filter. 2013 Dec 1
32 21703174 Cdc42 and Rac1 are major contributors to the saturated fatty acid-stimulated JNK pathway in hepatocytes. 2012 Jan 1
33 22038518 Coupling factor 6-induced activation of ecto-F1F(o) complex induces insulin resistance, mild glucose intolerance and elevated blood pressure in mice. 2012 Feb 2
34 22258022 Estrogen attenuates coupling factor 6-induced salt-sensitive hypertension and cardiac systolic dysfunction in mice. 2012 May 2
35 22330068 Small GTPases Rap1 and RhoA regulate superoxide formation by Rac1 GTPases activation during the phagocytosis of IgG-opsonized zymosans in macrophages. 2012 May 1 1
36 22820503 Role of RalA downstream of Rac1 in insulin-dependent glucose uptake in muscle cells. 2012 Nov 1
37 21266780 Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice. 2011 Feb 1
38 21358804 K-Ras mediated murine epidermal tumorigenesis is dependent upon and associated with elevated Rac1 activity. 2011 Feb 15 4
39 21565173 TRPC3-mediated Ca2+ influx contributes to Rac1-mediated production of reactive oxygen species in MLP-deficient mouse hearts. 2011 May 27 1
40 22243243 Epithelial-specific knockout of the Rac1 gene leads to enamel defects. 2011 Dec 2
41 19940064 CCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini. 2010 Mar 1
42 20184871 Neural crest cell-specific deletion of Rac1 results in defective cell-matrix interactions and severe craniofacial and cardiovascular malformations. 2010 Apr 15 1
43 19158396 The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion. 2009 Mar 1
44 21475797 Enhanced cytostatic activity of statins in mouse mammary carcinoma cells overexpressing β2-chimaerin. 2009 Jan-Feb 1
45 18059343 Differential motility of p190bcr-abl- and p210bcr-abl-expressing cells: respective roles of Vav and Bcr-Abl GEFs. 2008 Apr 24 1
46 18264091 Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2. 2008 Mar 1
47 18492274 Reduced paxillin expression contributes to the antimetastatic effect of 4-hydroxycoumarin on B16-F10 melanoma cells. 2008 May 20 1
48 19127770 [Fret-based single-molecule probes for monitoring induced activation of Rac, Cdc42 signaling pathways in living cells]. 2008 Oct 2
49 17196961 Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth. 2007 Feb 15 1
50 17202256 Enhancement of learning and memory after activation of cerebral Rho GTPases. 2007 Jan 9 1