Title : Src homology 2 domain containing protein 5 (SH2D5) binds the breakpoint cluster region protein, BCR, and regulates levels of Rac1-GTP.

Pub. Date : 2014 Dec 19

PMID : 25331951






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 siRNA-mediated depletion of SH2D5 in a neuroblastoma cell line, B35, induced a cell rounding phenotype correlated with low levels of activated Rac1-GTP, suggesting that SH2D5 affects Rac1-GTP levels. Guanosine Triphosphate Rac family small GTPase 1 Mus musculus
2 siRNA-mediated depletion of SH2D5 in a neuroblastoma cell line, B35, induced a cell rounding phenotype correlated with low levels of activated Rac1-GTP, suggesting that SH2D5 affects Rac1-GTP levels. Guanosine Triphosphate Rac family small GTPase 1 Mus musculus
3 siRNA-mediated depletion of SH2D5 in a neuroblastoma cell line, B35, induced a cell rounding phenotype correlated with low levels of activated Rac1-GTP, suggesting that SH2D5 affects Rac1-GTP levels. Guanosine Triphosphate Rac family small GTPase 1 Mus musculus
4 siRNA-mediated depletion of SH2D5 in a neuroblastoma cell line, B35, induced a cell rounding phenotype correlated with low levels of activated Rac1-GTP, suggesting that SH2D5 affects Rac1-GTP levels. Guanosine Triphosphate Rac family small GTPase 1 Mus musculus