Title : Vascular endothelial adrenomedullin-RAMP2 system is essential for vascular integrity and organ homeostasis.

Pub. Date : 2013 Feb 19

PMID : 23355623






1 Functional Relationships(s)
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1 We found that the AM-RAMP2 system regulates the Rac1-GTP/RhoA-GTP ratio and cortical actin formation and that a defect in this system causes the disruption of actin formation, leading to vascular and organ damage at the chronic stage after the gene deletion. Guanosine Triphosphate Rac family small GTPase 1 Mus musculus