Ristocetin

glycoprotein Ib platelet subunit alpha ; Homo sapiens







34 Article(s)
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1 34619770 A p.Arg127Gln variant in GPIbα LRR5 allosterically enhances affinity for VWF: a novel form of platelet-type VWD. 2022 Apr 12 1
2 33550910 Von Willebrand disease type 2B with a novel mutation in the VWF gene. 2021 Jan-Feb 1
3 30046704 Current issues in diagnosis and treatment of von Willebrand disease. 2018 Jan 1
4 30287479 Humanized GPIbα-von Willebrand factor interaction in the mouse. 2018 Oct 9 1
5 28142075 Platelet tissue factor activity and membrane cholesterol are increased in hypercholesterolemia and normalized by rosuvastatin, but not by atorvastatin. 2017 Feb 1
6 25677981 Shear-induced platelet receptor shedding by non-physiological high shear stress with short exposure time: glycoprotein Ibα and glycoprotein VI. 2015 Apr 1
7 22232560 Identification of a small molecule that modulates platelet glycoprotein Ib-von Willebrand factor interaction. 2012 Mar 16 4
8 22517896 O-linked glycosylation of von Willebrand factor modulates the interaction with platelet receptor glycoprotein Ib under static and shear stress conditions. 2012 Jul 5 1
9 22537243 Characterisation of von Willebrand factor A1 domain mutants I1416N and I1416T: correlation of clinical phenotype with flow-based platelet adhesion. 2012 Jul 1
10 22922961 Simultaneous exposure of sites in von Willebrand factor for glycoprotein Ib binding and ADAMTS13 cleavage: studies with ristocetin. 2012 Nov 1
11 23043782 Cloning of porcine platelet glycoprotein Ibα and comparison with the human homolog. 2012 Aug 1
12 23143686 Platelets with a W127X mutation in GPIX express sufficient residual amounts of GPIbα to support adhesion to von Willebrand factor and collagen. 2012 Dec 1
13 20216992 Role of glycoprotein Ibalpha mobility in platelet function. 2010 May 1
14 20443704 Engineering and characterization of a chimeric anti-platelet glycoprotein Ibalpha monoclonal antibody and preparation of its Fab fragment. 2010 Apr 1
15 20498367 Destabilization of the A1 domain in von Willebrand factor dissociates the A1A2A3 tri-domain and provokes spontaneous binding to glycoprotein Ibalpha and platelet activation under shear stress. 2010 Jul 23 1
16 19875727 Identification of a novel 14-3-3zeta binding site within the cytoplasmic domain of platelet glycoprotein Ibalpha that plays a key role in regulating the von Willebrand factor binding function of glycoprotein Ib-IX. 2009 Dec 4 1
17 18363340 Identification of peptide antagonists to glycoprotein Ibalpha that selectively inhibit von Willebrand factor dependent platelet aggregation. 2008 Apr 22 1
18 18815197 Novel point mutation in a leucine-rich repeat of the GPIbalpha chain of the platelet von Willebrand factor receptor, GPIb/IX/V, resulting in an inherited dominant form of Bernard-Soulier syndrome affecting two unrelated families: the N41H variant. 2008 Nov 1
19 17389010 Purified A2 domain of von Willebrand factor binds to the active conformation of von Willebrand factor and blocks the interaction with platelet glycoprotein Ibalpha. 2007 Jul 1
20 17598011 The A/T1381 polymorphism in the A1-domain of von Willebrand factor influences the affinity of von Willebrand factor for platelet glycoprotein Ibalpha. 2007 Jul 1
21 16978236 Molecular genetic analysis of a variant Bernard-Soulier syndrome due to compound heterozygosity for two novel glycoprotein Ibbeta mutations. 2006 Dec 1
22 15630508 Plasma glycocalicin as a source of GPIbalpha in the von Willebrand factor ristocetin cofactor ELISA. 2005 Jan 1
23 15809291 Role of chloride ions in modulation of the interaction between von Willebrand factor and ADAMTS-13. 2005 Jun 17 1
24 14754609 A sensitive ristocetin co-factor activity assay with recombinant glycoprotein Ibalpha for the diagnosis of patients with low von Willebrand factor levels. 2004 Jan 1
25 11279169 Tyrosine sulfation of glycoprotein I(b)alpha. Role of electrostatic interactions in von Willebrand factor binding. 2001 May 18 1
26 11341505 Fc-receptor dependent platelet aggregation induced by monoclonal antibodies against platelet glycoprotein Ib or von Willebrand factor. 2001 Apr 1
27 10027712 Down-regulation and redistribution of GPV/GPVf2, a subunit of von Willebrand factor receptor (GPIb/IX/V complex), on the surface membrane of thrombin-stimulated human platelets. 1999 Jan 1
28 9226170 Expression and functional characterization of an abnormal platelet membrane glycoprotein Ib alpha (Met239 --> Val) reported in patients with platelet-type von Willebrand disease. 1997 Jul 15 1
29 8664285 Mocarhagin, a novel cobra venom metalloproteinase, cleaves the platelet von Willebrand factor receptor glycoprotein Ibalpha. Identification of the sulfated tyrosine/anionic sequence Tyr-276-Glu-282 of glycoprotein Ibalpha as a binding site for von Willebrand factor and alpha-thrombin. 1996 Apr 16 1
30 7559492 Characterization of the unique mechanism mediating the shear-dependent binding of soluble von Willebrand factor to platelets. 1995 Oct 6 1
31 8463345 Expression of human platelet glycoprotein Ib alpha in transgenic mice. 1993 Apr 15 1
32 1651333 Site-directed mutagenesis of a soluble recombinant fragment of platelet glycoprotein Ib alpha demonstrating negatively charged residues involved in von Willebrand factor binding. 1991 Aug 15 1
33 2104618 Identification of a site in the alpha chain of platelet glycoprotein Ib that participates in von Willebrand factor binding. 1990 Jan 5 1
34 2822176 Calcium-dependent cysteine protease activity in the sera of patients with thrombotic thrombocytopenic purpura. 1987 Nov 1