Title : Purified A2 domain of von Willebrand factor binds to the active conformation of von Willebrand factor and blocks the interaction with platelet glycoprotein Ibalpha.

Pub. Date : 2007 Jul

PMID : 17389010






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The A2 domain polypeptide specifically recognizes the GPIbalpha-binding conformation in the A1 domain, as it only interacted with VWF activated by the modulator ristocetin or immobilized VWF. Ristocetin glycoprotein Ib platelet subunit alpha Homo sapiens