Spiperone

5-hydroxytryptamine receptor 1A ; Homo sapiens







23 Article(s)
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1 30347827 Oncotoxic Properties of Serotonin Transporter Inhibitors and 5-HT1A Receptor Ligands. 2018 Oct 20 2
2 11961140 Enhanced detection of receptor constitutive activity in the presence of regulators of G protein signaling: applications to the detection and analysis of inverse agonists and low-efficacy partial agonists. 2002 May 1
3 12052193 Ketanserin and spiperone as templates for novel serotonin 5-HT(2A) antagonists. 2002 Jun 1
4 12503636 Nad-299 antagonises 5-HT-stimulated and spiperone-inhibited [35S]GTPgammaS binding in cloned 5-HT1A receptors. 2002 Feb-Nov 1
5 10882396 5-HT(1A) receptor agonist-antagonist binding affinity difference as a measure of intrinsic activity in recombinant and native tissue systems. 2000 Jul 1
6 10496950 Regulation of G protein activation and effector modulation by fusion proteins between the human 5-hydroxytryptamine(1A) receptor and the alpha subunit of G(i1): differences in receptor-constitutive activity imparted by single amino acid substitutions in G(i1)alpha. 1999 Oct 4
7 9138675 Inhibition of the constitutive activity of human 5-HT1A receptors by the inverse agonist, spiperone but not the neutral antagonist, WAY 100,635. 1997 Mar 2
8 9176059 Protein kinase C activation by serotonin potentiates agonist-induced stimulation of cAMP production in cultured rat retinal pigment epithelial cells. 1997 Feb 1
9 9402034 Stimulated [35S]GTP gamma S binding by 5-HT1A receptor agonists in recombinant cell lines. Modulation of apparent efficacy by G-protein activation state. 1997 Nov 1
10 8979820 Serotonin modulates retinotectal and corticotectal convergence in the superior colliculus. 1996 1
11 9016944 Evidence for receptor subtype cross-talk in the mitogenic action of serotonin on human small-cell lung carcinoma cells. 1996 Dec 30 1
12 7620887 The action of 5-HT on calcium-dependent potassium channels and on the spinal locomotor network in lamprey is mediated by 5-HT1A-like receptors. 1995 Apr 24 1
13 7671319 Serotonin-induced calcium signaling via 5-HT1A receptors in human leukemia (K 562) cells. 1995 Oct 1 1
14 8566173 Mitogenic effect of serotonin in human small cell lung carcinoma cells via both 5-HT1A and 5-HT1D receptors. 1995 Oct 15 1
15 8461029 Characterization of recombinant human serotonin 5HT1A receptors expressed in Chinese hamster ovary cells. [3H]spiperone discriminates between the G-protein-coupled and -uncoupled forms. 1993 Mar 9 1
16 1320445 Activation of 5-HT1C/2 receptors depresses polysynaptic reflexes and excitatory amino acid-induced motoneuron responses in frog spinal cord. 1992 May 1 1
17 1403796 Comparison of 5-hydroxytryptamine1A-mediated hyperpolarization in CA1 and CA3 hippocampal pyramidal cells. 1992 Oct 1
18 1446239 The physiological effects of serotonin are mediated by the 5HT1A receptor in the cat's cerebellar cortex. 1992 Sep 25 1
19 1683291 Sympatholytic action of yohimbine mediated by 5-HT1A receptors. 1991 Jun 25 2
20 2138222 Characterization of the effects of activation of ventral medullary serotonin receptor subtypes on cardiovascular activity and respiratory motor outflow to the diaphragm and larynx. 1990 Feb 1
21 2141111 Changes in membrane potential of frog motoneurons induced by activation of serotonin receptor subtypes. 1990 1
22 2178032 Serotonin and GABA-induced depolarizations of frog primary afferent fibers. 1990 Nov 5 1
23 2969339 Electrophysiological evidence that spiperone is an antagonist of 5-HT1A receptors in the dorsal raphe nucleus. 1988 Apr 27 4