Title : Evidence for receptor subtype cross-talk in the mitogenic action of serotonin on human small-cell lung carcinoma cells.

Pub. Date : 1996 Dec 30

PMID : 9016944






1 Functional Relationships(s)
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1 Indeed, both GR127935 and the 5-HT1A antagonist spiperone shift the EC50 for the residual effect of 5-HT from approximately 300 to 120-150 nM, suggesting that blocking one receptor subtype may facilitate activation of the other. Spiperone 5-hydroxytryptamine receptor 1A Homo sapiens