Dexamethasone

AKT serine/threonine kinase 1 ; Homo sapiens







79 Article(s)
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51 22623960 Effects of fatty acid treatments on the dexamethasone-induced intramuscular lipid accumulation in chickens. 2012 1
52 22640031 Perifosine plus lenalidomide and dexamethasone in relapsed and relapsed/refractory multiple myeloma: a Phase I Multiple Myeloma Research Consortium study. 2012 Aug 2
53 22705301 β-Hydroxy-β-methylbutyrate (HMB) prevents dexamethasone-induced myotube atrophy. 2012 Jul 13 1
54 23060545 Glucocorticoids augment survival and proliferation of tumor cells. 2012 Oct 1
55 21209015 Protection against glucocorticoid-induced damage in human tenocytes by modulation of ERK, Akt, and forkhead signaling. 2011 Feb 2
56 21640799 Neurotoxicity induced by dexamethasone in the human neuroblastoma SH-SY5Y cell line can be prevented by folic acid. 2011 Sep 8 1
57 21828340 Cardiac proteasome activity in muscle ring finger-1 null mice at rest and following synthetic glucocorticoid treatment. 2011 Nov 1
58 21956421 Fibroblasts expressing the thyrotropin receptor overarch thyroid and orbit in Graves' disease. 2011 Dec 1
59 20005955 Dexamethasone protects human fibroblasts from apoptosis via an S1P3-receptor subtype dependent activation of PKB/Akt and Bcl XL. 2010 May 3
60 20022950 Dissecting the mechanism of insulin resistance using a novel heterodimerization strategy to activate Akt. 2010 Feb 19 1
61 20170512 Upstream molecular signaling pathways of p27(Kip1) expression: effects of 4-hydroxytamoxifen, dexamethasone, and retinoic acids. 2010 Feb 19 1
62 20534726 Effects of a novel selective androgen receptor modulator on dexamethasone-induced and hypogonadism-induced muscle atrophy. 2010 Aug 1
63 19390558 Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy. 2009 Jul 2
64 19442713 Dexamethasone protects auditory hair cells against TNFalpha-initiated apoptosis via activation of PI3K/Akt and NFkappaB signaling. 2009 Sep 3
65 18174290 Modulation of Dickkopf-1 attenuates glucocorticoid induction of osteoblast apoptosis, adipocytic differentiation, and bone mass loss. 2008 Apr 1
66 18292946 Dexamethasone interferes with trastuzumab-induced cell growth inhibition through restoration of AKT activity in BT-474 breast cancer cells. 2008 Mar 3
67 17537996 Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway. 2007 Sep 15 1
68 17595317 Glucocorticoid-induced degradation of glycogen synthase kinase-3 protein is triggered by serum- and glucocorticoid-induced protein kinase and Akt signaling and controls beta-catenin dynamics and tight junction formation in mammary epithelial tumor cells. 2007 Oct 1
69 16309671 Inhibition of PI3-kinase-Akt pathway enhances dexamethasone-induced apoptosis in a human follicular lymphoma cell line. 2006 Feb 1 2
70 15537647 Glucocorticoids inhibit the transcriptional activity of LEF/TCF in differentiating osteoblasts in a glycogen synthase kinase-3beta-dependent and -independent manner. 2005 Jan 21 4
71 15550386 Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway. 2005 Jan 28 1
72 15576458 Dexamethasone induces apoptosis in proliferative chondrocytes through activation of caspases and suppression of the Akt-phosphatidylinositol 3'-kinase signaling pathway. 2005 Mar 2
73 15927518 Insulin-like growth factor-I inhibits dexamethasone-induced proteolysis in cultured L6 myotubes through PI3K/Akt/GSK-3beta and PI3K/Akt/mTOR-dependent mechanisms. 2005 Oct 4
74 15047604 Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors. 2004 Apr 3
75 13679867 Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway. 2003 Sep 18 3
76 14555213 Pleiotropic anti-apoptotic activity of glucocorticoids in ovarian follicular cells. 2003 Oct 15 1
77 11857082 Role of the AKT kinase in expansion of multiple myeloma clones: effects on cytokine-dependent proliferative and survival responses. 2002 Feb 21 2
78 12173037 Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications. 2002 Aug 22 2
79 11593406 Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma. 2001 Sep 20 1