icariin

AKT serine/threonine kinase 1 ; Homo sapiens







24 Article(s)
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1 35114909 Proapoptotic Effect of Icariin on Human Ovarian Cancer Cells via the NF-[Formula: see text]B/PI3K-AKT Signaling Pathway: A Network Pharmacology-Directed Experimental Investigation. 2022 1
2 35442463 The mechanism of Epimedium in the treatment of coronary atherosclerotic heart disease based on network pharmacology, molecular docking, and in vitro studies. 2022 Apr 1
3 35514319 Icariin inhibits the malignant progression of lung cancer by affecting the PI3K/Akt pathway through the miR‑205‑5p/PTEN axis. 2022 Jun 2
4 34147477 IGF-1 receptor is involved in the regulatory effects of icariin and icaritin in astrocytes under basal conditions and after an inflammatory challenge. 2021 Sep 5 1
5 34306206 Icariin inhibits oral squamous cell carcinoma cell proliferation and induces apoptosis via inhibiting the NF-κB and PI3K/AKT pathways. 2021 Sep 3
6 32011040 Icariin inhibits proliferation, migration, and invasion of medulloblastoma DAOY cells by regulation of SPARC. 2020 Mar 2
7 32736044 Study on the regulatory mechanism and experimental verification of icariin for the treatment of ovarian cancer based on network pharmacology. 2020 Nov 15 2
8 32751124 3D Bioprinted Osteogenic Tissue Models for In Vitro Drug Screening. 2020 Jul 29 1
9 30551489 Icariin ameliorates cisplatin-induced cytotoxicity in human embryonic kidney 293 cells by suppressing ROS-mediated PI3K/Akt pathway. 2019 Jan 3
10 30551506 RETRACTED: Icariin inhibits cell proliferation, migration and invasion by down-regulation of microRNA-625-3p in thyroid cancer cells. 2019 Jan 1
11 30873034 Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways. 2019 2
12 31081049 Icariin enhances the chemosensitivity of cisplatin‑resistant ovarian cancer cells by suppressing autophagy via activation of the AKT/mTOR/ATG5 pathway. 2019 Jun 2
13 31091496 Icariin attenuate microcystin-LR-induced gap junction injury in Sertoli cells through suppression of Akt pathways. 2019 Aug 1
14 31424652 Icariin inhibits the growth of human cervical cancer cells by inducing apoptosis and autophagy by targeting mTOR/PI3K/AKT signalling pathway. 2019 May-Jun 2
15 31682849 Icariin induces apoptosis of human lung adenocarcinoma cells by activating the mitochondrial apoptotic pathway. 2019 Dec 15 2
16 31785072 The inhibitory function of icariin in cell model of benign prostatic hyperplasia by upregulation of miR-7. 2019 Nov 29 2
17 29767263 Icariin promotes wound healing by enhancing the migration and proliferation of keratinocytes via the AKT and ERK signaling pathway. 2018 Aug 5
18 28667862 Icariin exerts inhibitory effects on the growth and metastasis of KYSE70 human esophageal carcinoma cells via PI3K/AKT and STAT3 pathways. 2017 Sep 1
19 29259641 Icariin Prevents IL-1β-Induced Apoptosis in Human Nucleus Pulposus via the PI3K/AKT Pathway. 2017 3
20 27545131 [Icariin reduces S-nitrosogultathione induced endothelial cell apoptosis through modulating AKT/P53 pathway]. 2016 Aug 24 4
21 25747987 Icariin enhances cytotoxicity of doxorubicin in human multidrug-resistant osteosarcoma cells by inhibition of ABCB1 and down-regulation of the PI3K/Akt pathway. 2015 2
22 22088582 [Icariin and its pharmaceutical efficacy: research progress of molecular mechanism]. 2011 Nov 1
23 20416296 Involvement of androgen receptor in nitric oxide production induced by icariin in human umbilical vein endothelial cells. 2010 Jun 3 2
24 18789310 Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells. 2008 Nov 14 3