Iron

AKT serine/threonine kinase 1 ; Homo sapiens







27 Article(s)
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1 35484240 Apolipoprotein E potently inhibits ferroptosis by blocking ferritinophagy. 2022 Apr 28 1
2 32794021 Homocysteine-induced decrease in HUVEC cells' resistance to oxidative stress is mediated by Akt-dependent changes in iron metabolism. 2021 Apr 1
3 33821487 Role of iron and iron-related proteins in mesenchymal stem cells: Cellular and clinical aspects. 2021 Oct 1
4 34119884 Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling. 2021 Aug 1
5 32691165 Salicylidene acylhydrazides attenuate survival of SH-SY5Y neuroblastoma cells through affecting mitotic regulator Speedy/RINGO and ERK/MAPK-PI3K/AKT signaling. 2020 Jul 20 1
6 32828744 Taxifolin ameliorates iron overload-induced hepatocellular injury: Modulating PI3K/AKT and p38 MAPK signaling, inflammatory response, and hepatocellular regeneration. 2020 Oct 1 1
7 30873034 Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways. 2019 1
8 31213851 Deferoxamine-induced high expression of TfR1 and DMT1 enhanced iron uptake in triple-negative breast cancer cells by activating IL-6/PI3K/AKT pathway. 2019 3
9 29380557 hmSOD1 gene mutation-induced disturbance in iron metabolism is mediated by impairment of Akt signalling pathway. 2018 Jun 3
10 30267477 Proteomic Profiling of Iron-Treated Ovarian Cells Identifies AKT Activation that Modulates the CLEAR Network. 2018 Dec 2
11 28833753 Lactoferrin induces tropoelastin expression by activating the lipoprotein receptor-related protein 1-mediated phosphatidylinositol 3-kinase/Akt pathway in human dermal fibroblasts. 2017 Dec 1
12 26854247 Iron-induced oxidative stress activates AKT and ERK1/2 and decreases Dyrk1B and PRMT1 in neuroblastoma SH-SY5Y cells. 2016 Mar 2
13 25594146 Fimbrial cells exposure to catalytic iron mimics carcinogenic changes. 2015 Mar 1
14 26125440 Targeting cancer by binding iron: Dissecting cellular signaling pathways. 2015 Aug 7 1
15 32262777 Construction of a cancer-targeted nanosystem as a payload of iron complexes to reverse cancer multidrug resistance. 2015 Jun 7 1
16 24641804 Silencing of hepcidin enforces the apoptosis in iron-induced human cardiomyocytes. 2014 Mar 18 2
17 25239763 Brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor inhibit ferrous iron influx via divalent metal transporter 1 and iron regulatory protein 1 regulation in ventral mesencephalic neurons. 2014 Dec 1
18 23184650 Akt/Nrf2 activated upregulation of heme oxygenase-1 involves in the role of Rg1 against ferrous iron-induced neurotoxicity in SK-N-SH cells. 2013 Jul 1
19 22332905 Biochemical and molecular impacts of lactoferrin on small intestinal growth and development during early life. 2012 Jun 2
20 20947636 Iron-induced cardiac damage: role of apoptosis and deferasirox intervention. 2011 Jan 1
21 21672148 Rapamycin-induced hypophosphatemia and insulin resistance are associated with mTORC2 activation and Klotho expression. 2011 Aug 1
22 21742779 Chelation of lysosomal iron protects dopaminergic SH-SY5Y neuroblastoma cells from hydrogen peroxide toxicity by precluding autophagy and Akt dephosphorylation. 2011 Oct 1
23 19134195 Iron oxide nanoparticles induce human microvascular endothelial cell permeability through reactive oxygen species production and microtubule remodeling. 2009 Jan 9 2
24 17936676 Iron increases MMP-9 expression through activation of AP-1 via ERK/Akt pathway in human head and neck squamous carcinoma cells. 2008 Jun 4
25 18557926 TNF-alpha stimulates Akt by a distinct aPKC-dependent pathway in premalignant keratinocytes. 2008 Dec 1
26 16624972 Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity. 2006 Jul 3
27 10861214 Redox equilibria of manganese peroxidase from Phanerochaetes chrysosporium: functional role of residues on the proximal side of the haem pocket. 2000 Jul 1 1