Title : Biochemical and molecular impacts of lactoferrin on small intestinal growth and development during early life.

Pub. Date : 2012 Jun

PMID : 22332905






2 Functional Relationships(s)
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1 Mechanistically, the complex of Lf and LfR is internalized through clathrin-mediated endocytosis; both iron-free apo-Lf and iron-saturated holo-Lf activate the PI3K/Akt pathway, whereas only apo-Lf triggers ERK1/2 signaling. Iron AKT serine/threonine kinase 1 Homo sapiens
2 Mechanistically, the complex of Lf and LfR is internalized through clathrin-mediated endocytosis; both iron-free apo-Lf and iron-saturated holo-Lf activate the PI3K/Akt pathway, whereas only apo-Lf triggers ERK1/2 signaling. Iron AKT serine/threonine kinase 1 Homo sapiens