Estradiol

AKT serine/threonine kinase 1 ; Homo sapiens







127 Article(s)
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1 34478807 Effects of dual inhibition of AKT and ERK1/2 pathways on endometrial pro-inflammatory, hormonal, and epigenetic microenvironment in endometriosis. 2022 Jan 1 1
2 34821461 Low concentrations of 17β-estradiol exacerbate tamoxifen resistance in breast cancer treatment through membrane estrogen receptor-mediated signaling pathways. 2022 Mar 1
3 35055130 Chemerin Affects P4 and E2 Synthesis in the Porcine Endometrium during Early Pregnancy. 2022 Jan 15 1
4 35137666 E2 + norethisterone promotes the PI3K-AKT pathway via PGRMC1 to induce breast cancer cell proliferation. 2022 Feb 9 2
5 35425995 Estradiol inhibits autophagy of Mycobacterium tuberculosis‑infected 16HBE cells and controls the proliferation of intracellular Mycobacterium tuberculosis. 2022 Jun 1
6 32036721 Resveratrol Combined with 17β-Estradiol Prevents IL-1β Induced Apoptosis in Human Nucleus Pulposus Via The PI3K/AKT/Mtor and PI3K/AKT/GSK-3β Pathway. 2021 Aug 4
7 33466512 Apigenin, a Partial Antagonist of the Estrogen Receptor (ER), Inhibits ER-Positive Breast Cancer Cell Proliferation through Akt/FOXM1 Signaling. 2021 Jan 5 2
8 33665661 [17β-estradiol inhibits interleukin-1β-induced rat nucleus pulposus cell apoptosis through the PI3K/Akt/mTOR signal pathway]. 2021 Feb 25 1
9 33790784 17β-Estradiol Promotes Apoptosis of HepG2 Cells Caused by Oxidative Stress by Increasing Foxo3a Phosphorylation. 2021 1
10 33991616 Nuclear-translocation of ACLY induced by obesity-related factors enhances pyrimidine metabolism through regulating histone acetylation in endometrial cancer. 2021 Aug 10 1
11 34355701 Erratum: 17β-Estradiol Inhibites Tumor Necrosis Factor-α Induced Apoptosis of Human Nucleus Pulposus Cells via the PI3K/Akt Pathway. 2021 Aug 6 1
12 34371773 Schisandrol A Exhibits Estrogenic Activity via Estrogen Receptor α-Dependent Signaling Pathway in Estrogen Receptor-Positive Breast Cancer Cells. 2021 Jul 15 1
13 34407537 Sex Differences and Estradiol Effects in MAPK and Akt Cell Signaling across Subregions of the Hippocampus. 2021 Aug 18 1
14 34461224 Simvastatin modulates estrogen signaling in uterine leiomyoma via regulating receptor palmitoylation, trafficking and degradation. 2021 Oct 1
15 34503515 TRIB3 regulates FSHR expression in human granulosa cells under high levels of free fatty acids. 2021 Sep 9 1
16 34571963 Estradiol Inhibits Human Brain Vascular Pericyte Migration Activity: A Functional and Transcriptomic Analysis. 2021 Sep 4 1
17 34575683 GPR30 Activation by 17β-Estradiol Promotes p62 Phosphorylation and Increases Estrogen Receptor α Protein Expression by Inducing Its Release from a Complex Formed with KEAP1. 2021 Sep 11 2
18 34951372 β-Estradiol Induces Mitochondrial Apoptosis in Cervical Cancer Through the Suppression of AKT/NF-κB Signaling Pathway. 2021 Dec 22 4
19 31809475 17β-Estradiol Prevents Extracellular Matrix Degradation by Downregulating MMP3 Expression via PI3K/Akt/FOXO3 Pathway. 2020 Mar 1 2
20 32628929 β-estradiol adjusts intestinal function via ERβ and GPR30 mediated PI3K/AKT signaling activation to alleviate postmenopausal dyslipidemia. 2020 Oct 4
21 32665986 Atheroprotective effects of 17β-oestradiol are mediated by peroxisome proliferator-activated receptor γ in human coronary artery smooth muscle cells. 2020 1
22 33585221 Estrogen Receptor β1 Expression Patterns Have Different Effects on Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors' Treatment Response in Epidermal Growth Factor Receptor Mutant Lung Adenocarcinoma. 2020 1
23 31433456 Differential Actions of Estrogen Receptor α and β via Nongenomic Signaling in Human Prostate Stem and Progenitor Cells. 2019 Nov 1 1
24 31680862 Proteomic Identification of Pathways Responsible for the Estradiol Therapeutic Window in AD Animal Models. 2019 1
25 29330129 Estradiol up-regulates L-type Ca2+ channels via membrane-bound estrogen receptor/phosphoinositide-3-kinase/Akt/cAMP response element-binding protein signaling pathway. 2018 May 1
26 29608013 17β-Estradiol on the Expression of G-Protein Coupled Estrogen Receptor (GPER/GPR30) Mitophagy, and the PI3K/Akt Signaling Pathway in ATDC5 Chondrocytes In Vitro. 2018 Apr 2 2
27 29686616 Estradiol Activates PI3K/Akt/GSK3 Pathway Under Chronic Neurodegenerative Conditions Triggered by Perinatal Asphyxia. 2018 2
28 30584245 Estrogen affects the negative feedback loop of PTENP1-miR200c to inhibit PTEN expression in the development of endometrioid endometrial carcinoma. 2018 Dec 18 2
29 27222231 PI3K/Akt Activated by GPR30 and Src Regulates 17β-Estradiol-Induced Cultured Immature Boar Sertoli Cells Proliferation. 2017 Jan 7
30 27689466 Activation of estrogen receptor α by estradiol and cisplatin induces platinum-resistance in ovarian cancer cells. 2017 Sep 2 2
31 27870715 Posttranscriptional Control of PD-L1 Expression by 17β-Estradiol via PI3K/Akt Signaling Pathway in ERα-Positive Cancer Cell Lines. 2017 Feb 1
32 28098854 LSD1 sustains estrogen-driven endometrial carcinoma cell proliferation through the PI3K/AKT pathway via di-demethylating H3K9 of cyclin D1. 2017 Mar 1
33 28440394 G-protein-coupled receptor 30 mediates the effects of estrogen on endothelial cell tube formation in vitro. 2017 Jun 1
34 29282029 Docosahexaenoic acid reduces sterol regulatory element binding protein-1 and fatty acid synthase expression and inhibits cell proliferation by inhibiting pAkt signaling in a human breast cancer MCF-7 cell line. 2017 Dec 28 1
35 26938432 Estrogen Accelerates Cutaneous Wound Healing by Promoting Proliferation of Epidermal Keratinocytes via Erk/Akt Signaling Pathway. 2016 4
36 26969072 Lambda-cyhalothrin disrupts the up-regulation effect of 17β-estradiol on post-synaptic density 95 protein expression via estrogen receptor α-dependent Akt pathway. 2016 Mar 1
37 27188489 [Effects of estrogen on epidermis growth of mice and proliferation of human epidermal cell line HaCaT and its mechanism]. 2016 May 1
38 27255147 17β-Estradiol Reverses Leptin-Inducing Ovarian Cancer Cell Migration by the PI3K/Akt Signaling Pathway. 2016 Nov 1
39 27349969 Effects of estradiol on VEGF and bFGF by Akt in endometrial cancer cells are mediated through the NF-κB pathway. 2016 Aug 1
40 27847386 17β-Estradiol Inhibites Tumor Necrosis Factor-α Induced Apoptosis of Human Nucleus Pulposus Cells via the PI3K/Akt Pathway. 2016 Nov 12 1
41 25701261 Insulin priming effect on estradiol-induced breast cancer metabolism and growth. 2015 1
42 25739982 mTOR is involved in 17β-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1, and CCNE1. 2015 Apr 2
43 25765937 Oestrogen receptor alpha in pulmonary hypertension. 2015 May 1 1
44 26884863 17β-estradiol activates mTOR in chondrocytes by AKT-dependent and AKT-independent signaling pathways. 2015 2
45 24396487 Estrogen protects SGC7901 cells from endoplasmic reticulum stress-induced apoptosis by the Akt pathway. 2014 Feb 2
46 24611062 Estrogen Regulates Protein Synthesis and Actin Polymerization in Hippocampal Neurons through Different Molecular Mechanisms. 2014 1
47 24848710 IGF1R signaling is necessary for FSH-induced activation of AKT and differentiation of human Cumulus granulosa cells. 2014 Aug 1
48 25138535 Ubiquitin-activating enzyme is necessary for 17β-estradiol-induced breast cancer cell proliferation and migration. 2014 Aug 1
49 25189390 Nitric oxide as a mediator of estrogen effects in osteocytes. 2014 2
50 25216292 Estrogen stimulates the invasion of ovarian cancer cells via activation of the PI3K/AKT pathway and regulation of its downstream targets E‑cadherin and α‑actinin‑4. 2014 Nov 1