Title : Activation of estrogen receptor α by estradiol and cisplatin induces platinum-resistance in ovarian cancer cells.

Pub. Date : 2017 Sep 2

PMID : 27689466






2 Functional Relationships(s)
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1 The proliferation assay showed that 17beta-estradiol (E2) induced cell proliferation via activation of Akt and extracellular signal-regulated kinase (ERK) cascades, while shRNA mediated downregulation of ERalpha inhibited the cell proliferation. Estradiol AKT serine/threonine kinase 1 Homo sapiens
2 The proliferation assay showed that 17beta-estradiol (E2) induced cell proliferation via activation of Akt and extracellular signal-regulated kinase (ERK) cascades, while shRNA mediated downregulation of ERalpha inhibited the cell proliferation. Estradiol AKT serine/threonine kinase 1 Homo sapiens