Title : Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration.

Pub. Date : 2011 Sep 27

PMID : 21954290






1 Functional Relationships(s)
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1 These results suggest a mechanism by which multiple receptors activate PI3K through tyrosine phosphorylation of GIV, thereby making the GIV-PI3K interaction a potential therapeutic target within the PI3K-Akt pathway. Tyrosine AKT serine/threonine kinase 1 Homo sapiens