Title : The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species.

Pub. Date : 2009 Sep 18

PMID : 19633358






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Collectively, these data suggest that VEGF leads to a Rac-mediated generation of ROS, which, in turn, elevates the tyrosine phosphorylation of VE-cadherin and beta-catenin, ultimately regulating adherens junction integrity. Tyrosine AKT serine/threonine kinase 1 Homo sapiens