pi(4,5)p2

AKT serine/threonine kinase 1 ; Homo sapiens







10 Article(s)
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1 33743346 Expression of PRIP, a phosphatidylinositol 4,5-bisphosphate binding protein, attenuates PI3K/AKT signaling and suppresses tumor growth in a xenograft mouse model. 2021 May 7 1
2 33947796 Structural analysis of the PTEN:P-Rex2 signaling complex reveals how cancer-associated mutations coordinate to hyperactivate Rac1. 2021 May 4 1
3 32593716 Dual Function of PI(4,5)P2 in Insulin-Regulated Exocytic Trafficking of GLUT4 in Adipocytes. 2020 Jul 24 1
4 30692200 T cells transduce T-cell receptor signal strength by generating different phosphatidylinositols. 2019 Mar 29 1
5 29359392 Importance of phosphoinositide binding by human β-defensin 3 for Akt-dependent cytokine induction. 2018 Jan 2
6 26212011 Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer. 2016 Apr 28 1
7 27601656 In B cells, phosphatidylinositol 5-phosphate 4-kinase-α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signaling. 2016 Sep 20 1
8 27819060 The Hidden Conundrum of Phosphoinositide Signaling in Cancer. 2016 Jul 1
9 24662006 Dysregulation of the IGF-I/PI3K/AKT/mTOR signaling pathway in autism spectrum disorders. 2014 Jun 1
10 23443536 PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma. 2013 1