Pub. Date : 2018 Jan
PMID : 29359392
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recently, we have shown that HBD-3 can enter mammalian cells and bind to inner membrane phosphoinositide 4,5-bisphosphate [PI(4,5)P2], an important second lipid messenger of PLC and PI3K-Akt pathways. | pi(4,5)p2 | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | In this study, we report that the interaction of HBD-3 with PI(4,5)P2 is important for PI3K-Akt-NF-kappaBeta-mediated induction of tumor necrosis factor and interleukin-6. | pi(4,5)p2 | AKT serine/threonine kinase 1 | Homo sapiens |