Title : T cells transduce T-cell receptor signal strength by generating different phosphatidylinositols.

Pub. Date : 2019 Mar 29

PMID : 30692200






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A proteomics screen revealed that focal adhesion kinase bound PI(4,5)P2, biochemical assays disclosed that focal adhesion kinase is preferentially activated by weak TCR signals and is required for optimal Treg induction, and further biochemical experiments revealed how TCR signaling strength regulates AKT activation. pi(4,5)p2 AKT serine/threonine kinase 1 Homo sapiens