pifithrin

transformation related protein 53, pseudogene ; Mus musculus







73 Article(s)
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1 35143901 Urea transporter B downregulates polyamines levels in melanoma B16 cells via p53 activation. 2022 May 1
2 35203361 p53 in Proximal Tubules Mediates Chronic Kidney Problems after Cisplatin Treatment. 2022 Feb 17 2
3 35418568 Downregulation of REST in the cochlea contributes to age-related hearing loss via the p53 apoptosis pathway. 2022 Apr 13 1
4 33162236 Multiple transcriptomic profiling: p53 signaling pathway is involved in DEHP-induced prepubertal testicular injury via promoting cell apoptosis and inhibiting cell proliferation of Leydig cells. 2021 Mar 15 1
5 33302638 Ligustrazine induces the colorectal cancer cells apoptosis via p53-dependent mitochondrial pathway and cell cycle arrest at the G0/G1 phase. 2021 Feb 2
6 34285767 PIN1 Protects Hair Cells and Auditory HEI-OC1 Cells against Senescence by Inhibiting the PI3K/Akt/mTOR Pathway. 2021 1
7 34746182 Proximal Tubule p53 in Cold Storage/Transplantation-Associated Kidney Injury and Renal Graft Dysfunction. 2021 1
8 34864826 Targeting ERK induced cell death and p53/ROS-dependent protective autophagy in colorectal cancer. 2021 Dec 4 1
9 31618665 Triptolide dysregulates glucose uptake via inhibition of IKKβ-NF-κB pathway by p53 activation in cardiomyocytes. 2020 Jan 1
10 32048816 P53/PANK1/miR-107 signalling pathway spans the gap between metabolic reprogramming and insulin resistance induced by high-fat diet. 2020 Mar 1
11 32299471 α-Synucleinopathy associated c-Abl activation causes p53-dependent autophagy impairment. 2020 Apr 16 1
12 32741018 Novel evidence for retinoic acid-induced G (Rig-G) as a tumor suppressor by activating p53 signaling pathway in lung cancer. 2020 Sep 1
13 33299335 p53 Mediates GnRH Secretion via Lin28/let-7 System in GT1-7 Cells. 2020 1
14 31069753 Pifithrin-Alpha Reduces Methamphetamine Neurotoxicity in Cultured Dopaminergic Neurons. 2019 Aug 2
15 31148231 p53 induces miR-199a-3p to suppress mechanistic target of rapamycin activation in cisplatin-induced acute kidney injury. 2019 Oct 1
16 31377450 Dysregulation of p53 and Parkin Induce Mitochondrial Dysfunction and Leads to the Diabetic Neuropathic Pain. 2019 Sep 15 2
17 31906131 The Use of High-Throughput Transcriptomics to Identify Pathways with Therapeutic Significance in Podocytes. 2019 Dec 31 1
18 29401620 FGF21 is induced in cisplatin nephrotoxicity to protect against kidney tubular cell injury. 2018 Jun 2
19 29704532 MDM2 controls NRF2 antioxidant activity in prevention of diabetic kidney disease. 2018 Aug 1
20 29890190 Dysregulation and restoration of homeostatic network plasticity in fragile X syndrome mice. 2018 Aug 1
21 30112029 Echinacoside suppresses dexamethasone-induced growth inhibition and apoptosis in osteoblastic MC3T3-E1 cells. 2018 Aug 1
22 30126780 Tumor suppressor protein p53 negatively regulates ischemia-induced angiogenesis and arteriogenesis. 2018 Dec 2
23 27194299 Anesthetic Isoflurane Induces DNA Damage Through Oxidative Stress and p53 Pathway. 2017 Jul 1
24 27622990 Induction of microRNA-17-5p by p53 protects against renal ischemia-reperfusion injury by targeting death receptor 6. 2017 Jan 1
25 27879267 Pifithrin-μ Prevents Cisplatin-Induced Chemobrain by Preserving Neuronal Mitochondrial Function. 2017 Feb 1 1
26 28145533 Induction of Bex genes by curcumin is associated with apoptosis and activation of p53 in N2a neuroblastoma cells. 2017 Feb 1 1
27 28320710 Myeloid p53 regulates macrophage polarization and venous thrombus resolution by inflammatory vascular remodeling in mice. 2017 Jun 15 1
28 28663058 The induction of tumour suppressor protein P53 limits the entry of cells into the pluripotent inner cell mass lineage in the mouse embryo. 2017 Sep 15 1
29 28762569 GA-Binding Protein Alpha Is Involved in the Survival of Mouse Embryonic Stem Cells. 2017 Nov 1
30 26563498 N-Methyl, N-propynyl-2-phenylethylamine (MPPE), a Selegiline Analog, Attenuates MPTP-induced Dopaminergic Toxicity with Guaranteed Behavioral Safety: Involvement of Inhibitions of Mitochondrial Oxidative Burdens and p53 Gene-elicited Pro-apoptotic Change. 2016 Nov 1
31 26784190 Metformin Restores Parkin-Mediated Mitophagy, Suppressed by Cytosolic p53. 2016 Jan 16 1
32 27016419 Numb contributes to renal fibrosis by promoting tubular epithelial cell cycle arrest at G2/M. 2016 May 3 2
33 27133769 mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis. 2016 Aug 1
34 27748853 Pterostilbene inhibits hepatocellular carcinoma through p53/SOD2/ROS-mediated mitochondrial apoptosis. 2016 Dec 1
35 24963915 Hyperglycemia, p53, and mitochondrial pathway of apoptosis are involved in the susceptibility of diabetic models to ischemic acute kidney injury. 2015 Jan 1
36 25542456 Pifithrin-α ameliorates resveratrol-induced two-cell block in mouse preimplantation embryos in vitro. 2015 Mar 15 2
37 26473292 Prevention of chemotherapy-induced peripheral neuropathy by the small-molecule inhibitor pifithrin-μ. 2015 Nov 1
38 26523514 Vaginal LPS changed gene transcriptional regulation response to ischemic reperfusion and increased vulnerability of fetal brain hemorrhage. 2015 Dec 4-11 1
39 24070868 p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin. 2014 Feb 1 4
40 24516131 Inhibition of p53 preserves Parkin-mediated mitophagy and pancreatic β-cell function in diabetes. 2014 Feb 25 1
41 24916697 Cisplatin-induced renal injury is independently mediated by OCT2 and p53. 2014 Aug 1 2
42 24948812 Nrf2 upregulates ATP binding cassette transporter expression and activity at the blood-brain and blood-spinal cord barriers. 2014 Jun 18 1
43 25329663 Intrauterine ischemic reperfusion switches the fetal transcriptional pattern from HIF-1α- to P53-dependent regulation in the murine brain. 2014 1
44 28962260 Mechanisms linked to differences in the mutagenic potential of 1,3-dinitropyrene and 1,8-dinitropyrene. 2014 1
45 23222126 p53 is renoprotective after ischemic kidney injury by reducing inflammation. 2013 Jan 3
46 23454130 Pifithrin-α, a pharmacological inhibitor of p53, downregulates lipopolysaccharide-induced nitric oxide production via impairment of the MyD88-independent pathway. 2013 Apr 1
47 23500643 Mouse embryonic stem cells undergo charontosis, a novel programmed cell death pathway dependent upon cathepsins, p53, and EndoG, in response to etoposide treatment. 2013 May 2
48 22436728 MicroRNA-34a upregulation during seizure-induced neuronal death. 2012 Mar 22 1
49 23022514 Mechanisms for ribotoxin-induced ribosomal RNA cleavage. 2012 Nov 15 1
50 23123091 Involvement of PTEN in TPA-mediated p53-activation in mouse skin epidermal JB6 cells. 2012 Nov 30 1