Title : Cisplatin-induced renal injury is independently mediated by OCT2 and p53.

Pub. Date : 2014 Aug 1

PMID : 24916697






2 Functional Relationships(s)
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1 We found that pifithrin-alpha, an inhibitor of p53-dependent transcriptional activation, inhibits Oct2 and can mimic the lack of nephrotoxicity observed in p53(-/-)/Oct1/2(-/-)mice. pifithrin transformation related protein 53, pseudogene Mus musculus
2 We found that pifithrin-alpha, an inhibitor of p53-dependent transcriptional activation, inhibits Oct2 and can mimic the lack of nephrotoxicity observed in p53(-/-)/Oct1/2(-/-)mice. pifithrin transformation related protein 53, pseudogene Mus musculus