Title : Pifithrin-μ Prevents Cisplatin-Induced Chemobrain by Preserving Neuronal Mitochondrial Function.

Pub. Date : 2017 Feb 1

PMID : 27879267






1 Functional Relationships(s)
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1 Prompted by the hypothesis that neuronal mitochondrial dysfunction underlies chemotherapy-induced cognitive impairment (CICI), we explored the efficacy of administering the small-molecule pifithrin (PFT)-mu, an inhibitor of mitochondrial p53 accumulation, in preventing CICI. pifithrin transformation related protein 53, pseudogene Mus musculus