Title : p53 induces miR-199a-3p to suppress mechanistic target of rapamycin activation in cisplatin-induced acute kidney injury.

Pub. Date : 2019 Oct

PMID : 31148231






1 Functional Relationships(s)
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1 We find that p53 was upregulated in cisplatin-induced AKI, yet, pifithrin-alpha inhibites the p53 expression to attenuated renal injury and cell apoptosis both in vivo cisplatin-induced AKI mice and in vitro HK-2 human renal tubular epithelial cells. pifithrin transformation related protein 53, pseudogene Mus musculus