Fluorouracil

interferon alpha 1 ; Homo sapiens







125 Article(s)
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1 29719589 Combination of interferon-expressing oncolytic adenovirus with chemotherapy and radiation is highly synergistic in hamster model of pancreatic cancer. 2018 Apr 6 1
2 28591290 Adjuvant treatment or primary topical monotherapy for ocular surface squamous neoplasia: a systematic review. 2017 Mar-Apr 3
3 23457527 Identification of the genes chemosensitizing hepatocellular carcinoma cells to interferon-α/5-fluorouracil and their clinical significance. 2013 1
4 24100378 Protein-bound polysaccharide-K augments the anticancer effect of fluoropyrimidine derivatives possibly by lowering dihydropyrimidine dehydrogenase expression in gastrointestinal cancers. 2013 Dec 1
5 24219283 Comparative in vitro evaluation of transportability and toxicity of capecitabine and its metabolites in cells derived from normal human kidney and renal cancers. 2013 Dec 3
6 24367220 Type 1 interferon receptor in peripheral blood mononuclear cells may predict response to intra-arterial 5-fluorouracil + interferon therapy for advanced hepatocellular carcinoma. 2011 6
7 20407444 Insulin-like growth factor-binding protein 7 alters the sensitivity to interferon-based anticancer therapy in hepatocellular carcinoma cells. 2010 May 11 1
8 20616597 Treatment of advanced hepatocellular carcinoma: intraarterial infusion chemotherapy combined with interferon. 2010 Jul 1
9 20978511 MicroRNA-21 induces resistance to the anti-tumour effect of interferon-α/5-fluorouracil in hepatocellular carcinoma cells. 2010 Nov 9 1
10 19401692 Activation of Wnt/beta-catenin signalling pathway induces chemoresistance to interferon-alpha/5-fluorouracil combination therapy for hepatocellular carcinoma. 2009 May 19 1
11 19821965 Combination of interferon-alpha and 5-fluorouracil inhibits endothelial cell growth directly and by regulation of angiogenic factors released by tumor cells. 2009 Oct 12 2
12 18996727 Chemoradioimmunotherapy with 5-fluorouracil, cisplatin and interferon-alpha in pancreatic and periampullary cancer: results of a feasibility study. 2008 Dec 1
13 17045692 Role of the Fas/FasL pathway in combination therapy with interferon-alpha and fluorouracil against hepatocellular carcinoma in vitro. 2007 Jan 6
14 17275163 Synergy of interferon-alpha and 5-fluorouracil in human renal cell carcinoma requires p53 activity. 2007 Oct 1
15 17671767 Complete remission of hepatocellular carcinoma with portal vein tumor thrombus and lymph node metastases by arterial infusion of 5-fluorouracil and interferon-alpha combination therapy following hepatic resection. 2007 Jun 1
16 17699726 Alteration of dihydropyrimidine dehydrogenase expression by IFN-alpha affects the antiproliferative effects of 5-fluorouracil in human hepatocellular carcinoma cells. 2007 Aug 2
17 17941012 Interferon-alpha and 5-fluorouracil combination therapy after palliative hepatic resection in patients with advanced hepatocellular carcinoma, portal venous tumor thrombus in the major trunk, and multiple nodules. 2007 Dec 1 1
18 17988526 [Interferon alpha enhances the sensitivity of SMMC-7721 hepatocellular carcinoma cells to 5'-deoxy-5-fluorouridine related to up-regulation of thymidine phosphorylase]. 2007 Aug 14 1
19 16490547 Interferon receptors and the caspase cascade regulate the antitumor effects of interferons on human pancreatic cancer cell lines. 2006 Mar 1
20 16706824 Antiproliferative effects of 5-fluorouracil and interferon-alpha in combination on a hepatocellular carcinoma cell line in vitro and in vivo. 2006 Jan 1
21 17016659 Combination of 5-FU and IFNalpha enhances IFN signaling pathway and caspase-8 activity, resulting in marked apoptosis in hepatoma cell lines. 2006 Nov 3
22 17088986 The up-regulation of type I interferon receptor gene plays a key role in hepatocellular carcinoma cells in the synergistic antiproliferative effect by 5-fluorouracil and interferon-alpha. 2006 Dec 3
23 17099286 Role of p53 in the inhibitory effects of interferon-alpha subtypes on proliferation of hepatocellular carcinoma cells. 2006 Oct 2
24 15698412 Consensus interferon enhances the anti-proliferative effect of 5-fluorouracil on human hepatoma cells via downregulation of dihydropyrimidine dehydrogenase expression. 2005 Feb 1
25 15709199 Combination of IFN-alpha and 5-fluorouracil induces apoptosis through IFN-alpha/beta receptor in human hepatocellular carcinoma cells. 2005 Feb 1 3
26 15937643 Interferons upregulate thymidine phosphorylase expression via JAK-STAT-dependent transcriptional activation and mRNA stabilization in human glioblastoma cells. 2005 May 2
27 16041207 Increase of survival benefit in advanced resectable colon cancer by extent of adjuvant treatment: results of a randomized trial comparing modulation of 5-FU + levamisole with folinic acid or with interferon-alpha. 2005 Aug 1
28 16101138 5-Fluorouracil up-regulates interferon pathway gene expression in esophageal cancer cells. 2005 Sep-Oct 6
29 16149157 Successful treatment of advanced hepatocellular carcinoma by combined administration of 5-fluorouracil and pegylated interferon-alpha. 2005 Sep 14 4
30 16184937 [A case of colon cancer with liver and lung metastases-efficacy of CPT-11/5-FU/l-LV (IFL) as part of ambulatory treatment]. 2005 Sep 2
31 15082204 Interleukin-2, interferon-alpha and 5-fluorouracil immunotherapy for metastatic renal cell carcinoma: the all Ireland experience. 2004 May 2
32 15492816 Genes associated with human hepatocellular carcinoma cell chemosensitivity to 5-fluorouracil plus interferon-alpha combination chemotherapy. 2004 Nov 2
33 15585621 Partial contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/TRAIL receptor pathway to antitumor effects of interferon-alpha/5-fluorouracil against Hepatocellular Carcinoma. 2004 Dec 1 1
34 12209689 Thirteen-year, long-term efficacy of interferon 2alpha and interleukin 2-based home therapy in patients with advanced renal cell carcinoma. 2002 Sep 1 1
35 12402433 [A case of recurrent hepatocellular carcinoma successfully treated with a combination therapy of interferon-alpha and intravenous continuous infusion of 5-fluorouracil]. 2002 Oct 2
36 11370832 Drug action on poly(A) polymerase activity and isoforms during U937 cell apoptosis. 2001 Mar 1
37 11419451 Toxicity and effects of adjuvant therapy in colon cancer: results of the German prospective, controlled randomized multicenter trial FOGT-1. 2001 May-Jun 1
38 10637237 Enhancement of fluorouracil uptake in human colorectal and gastric cancers by interferon or by high-dose methotrexate: An in vivo human study using noninvasive (19)F-magnetic resonance spectroscopy. 2000 Jan 5
39 10762745 A phase II study of ifosfamide, 5-fluorouracil and leucovorin in patients with recurrent nasopharyngeal carcinoma previously treated with platinum chemotherapy. 2000 Apr 1
40 10883892 Anticancer drug action on poly(A) polymerase activity and isoforms during HeLa and WISH cell apoptosis. 2000 Apr-Jun 1
41 10901374 Induction of thymidine phosphorylase as a pharmacodynamic end-point in patients with advanced carcinoma treated with 5-fluorouracil, folinic acid and interferon alpha. 2000 Jul 2
42 10914738 Augmentation of antitumor activity of 5-fluorouracil by interferon alpha is associated with up-regulation of p27Kip1 in human hepatocellular carcinoma cells. 2000 Jul 2
43 10023694 A phase II study of 5-fluorouracil, leucovorin, and interferon-alpha in the treatment of patients with metastatic or recurrent gastric carcinoma: an Eastern Cooperative Oncology Group study (E5292). 1999 Jan 15 2
44 10334547 Tumor, normal tissue, and plasma pharmacokinetic studies of fluorouracil biomodulation with N-phosphonacetyl-L-aspartate, folinic acid, and interferon alfa. 1999 May 1
45 10339671 Enhancement of 5-fluorouracil cytotoxicity on human colon cancer cells by retrovirus-mediated interferon-alpha gene transfer. 1999 Jun 1
46 10412941 Biomodulation of 5-fluorouracil by interferon-alpha in human renal carcinoma cells: relationship to the expression of thymidine phosphorylase. 1999 7
47 10440197 Phase I-II study of 5-fluorouracil, recombinant interferon alpha2a, and cisplatin in combination with external beam radiation therapy followed by surgery in patients with locally advanced carcinoma of the esophagus. 1999 Aug 1
48 10448286 Biochemical modulation of 5-fluorouracil by leucovorin with or without interferon-alpha-2c in patients with advanced colorectal cancer: final results of a randomised phase III study. 1999 Mar 1
49 10606259 Interferons as biomodulators of fluoropyrimidines in the treatment of colorectal cancer. 1999 Dec 1
50 9463483 Modulation of fluorouracil cytotoxicity by interferon-alpha and -gamma. 1998 Feb 2