Title : Combination of interferon-alpha and 5-fluorouracil inhibits endothelial cell growth directly and by regulation of angiogenic factors released by tumor cells.

Pub. Date : 2009 Oct 12

PMID : 19821965






2 Functional Relationships(s)
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1 BACKGROUND: The combination therapy of interferon (IFN)-alpha and 5-fluorouracil (5-FU) improved the prognosis of the patients with hepatocellular carcinoma (HCC). Fluorouracil interferon alpha 1 Homo sapiens
2 RESULTS: IFN-alpha and 5-FU alone had anti-proliferative properties on HUVEC and their combination significantly inhibited the growth (compared with control, 5-FU or IFN alone). Fluorouracil interferon alpha 1 Homo sapiens