Fluorouracil

interferon alpha 1 ; Homo sapiens







125 Article(s)
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51 9508190 Phase III trial of modulation of cisplatin/fluorouracil chemotherapy by interferon alfa-2b in patients with recurrent or metastatic head and neck cancer. Head and Neck Interferon Cooperative Study Group. 1998 Mar 1
52 9589033 Biomodulation of Fluorouracil in colorectal cancer. 1998 2
53 9619746 5-Fluorouracil plus interferon alpha-2a compared to 5-fluorouracil alone in the treatment of advanced colon carcinoma: a multicentric randomized study. 1998 2
54 9726437 Biomodulation with sequential intravenous IFN-alpha2b and 5-fluorouracil as second-line treatment in patients with advanced colorectal cancer. 1998 Aug 1
55 9839521 Adjuvant 5-fluorouracil and leucovorin with or without interferon alfa-2a in colon carcinoma: National Surgical Adjuvant Breast and Bowel Project protocol C-05. 1998 Dec 2 1
56 10388104 Gene Regulation and Clinical Roles for Interferons in Neoplastic Diseases. 1998 4
57 9020295 Treatment of advanced pancreatic adenocarcinoma with 5-FU, leucovorin, interferon-alpha-2b, and cisplatin. 1997 Feb 4
58 9070485 Bimonthly high dose leucovorin and 5-fluorouracil 48-hour infusion with interferon-alpha-2a in patients with advanced colorectal carcinoma. Groupe d'Etude et de Recherche sur les Cancers de l'Ovaire et Digestifs (GERCOD). 1997 Mar 15 6
59 9155534 Biochemical mechanisms of interferon modulation of 5-fluorouracil activity in colon cancer cells. 1997 Mar 7
60 9815792 A pilot study of gamma-1b-interferon in combination with fluorouracil, leucovorin, and alpha-2a-interferon. 1997 Jul 6
61 9815814 Combination therapy with 5-fluorouracil and IFN-alpha2a induces a nonrandom increase in DNA fragments of less than 3 megabases in HT29 colon carcinoma cells. 1997 Aug 1
62 8620460 Synergistic inhibitory effects of interferon-alpha and 5-fluorouracil in meningioma cells in vitro. 1996 Feb 27 1
63 8646722 Phase II clinical trial with 5-fluorouracil, recombinant interferon-alpha-2b, and cisplatin for patients with metastatic or regionally advanced carcinoma of the esophagus. 1996 Jul 1 2
64 8758262 Phase II trial of N-(phosphonacetyl)-L-aspartate (PALA), 5-fluorouracil and recombinant interferon-alpha-2b in patients with advanced gastric carcinoma. 1996 Jun 1
65 8823494 Effect of interferon on 5-fluorouracil-induced perturbations in pools of deoxynucleotide triphosphates and DNA strand breaks. 1996 6
66 8824349 Phase I trial of high-dose infusional hydroxyurea, high-dose infusional 5-fluorouracil and recombinant interferon-alpha-2a in patients with advanced malignancies. 1996 2
67 8826868 A phase II randomised trial of 5-fluorouracil with or without interferon alpha-2a in advanced colorectal cancer. 1996 Sep 2
68 8862717 A phase I trial of 5-fluorouracil, leucovorin and interferon-alpha 2b administered by 24 h infusion in metastatic colorectal carcinoma. 1996 Jul 1
69 8874326 Phase III randomized study to compare interferon alfa-2a in combination with fluorouracil versus fluorouracil alone in patients with advanced colorectal cancer. 1996 Oct 1
70 8879370 5-Fluorouracil versus 5-fluorouracil plus alpha-interferon as treatment of metastatic colorectal carcinoma. A randomized study. 1996 Aug 1
71 8931668 Phase II trial of prolonged continuous infusion of 5-fluorouracil and interferon-alpha in patients with advanced pancreatic cancer. Eastern Cooperative Oncology Group Protocol 3292. 1996 Dec 3
72 9229325 High-dose infusional 5-fluorouracil combination therapy of metastatic gastric and colorectal cancer. 1996 Summer 1
73 7577043 The role of interferon-alpha as a modulator of fluorouracil and leucovorin. 1995 Jul-Aug 2
74 7597304 Biochemical modulation of cytotoxic drugs by cytokines: molecular mechanisms in experimental oncology. 1995 7
75 7611752 [Biomodulation of 5-fluorouracil by interferon]. 1995 Jul 6
76 7627962 5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression. 1995 Aug 15 1
77 7634247 Interferon-alpha-induced protection of renal cell cancer cell line from lysis by natural killer cells and increase of susceptibility by treatment with 5-fluorouracil. 1995 Aug 1 2
78 7642571 Thymidine phosphorylase mediates the sensitivity of human colon carcinoma cells to 5-fluorouracil. 1995 Aug 11 5
79 7646900 Treatment of advanced colorectal cancer with 5-fluorouracil and interferon-alpha: an overview of clinical trials. 1995 Jun 1
80 7666089 Impact of protracted venous infusion fluorouracil with or without interferon alfa-2b on tumor response, survival, and quality of life in advanced colorectal cancer. 1995 Sep 1
81 7669711 Interferon-alpha does not improve the antineoplastic efficacy of high-dose infusional 5-fluorouracil plus folinic acid in advanced colorectal cancer. First results of a randomized multicenter study by the Association of Medical Oncology of the German Cancer Society (AIO). 1995 May 1
82 7850703 5-Fluorouracil/leucovorin/interferon alpha-2a in patients with advanced colorectal cancer. Effects of maintenance therapy on remission duration. 1995 Mar 1 1
83 7882458 A phase I study of recombinant human interferon alpha-2b combined with 5-fluorouracil and cisplatin in patients with advanced cancer. 1995 3
84 8542247 Pharmacokinetic interaction of 5-fluorouracil and interferon alpha-2b with or without folinic acid. 1995 Mar 2
85 21556603 Long-term microcalorimetric findings in renal-cell carcinoma exposed to interferon-alpha-2a, interleukin-2 and 5-Fluorouracil. 1995 Apr 1
86 7516637 Cisplatin, 5-fluorouracil and alpha interferon in non small cell lung carcinoma: a toxicity study. 1994 Mar-Apr 1
87 7812360 Phase I study of interleukin-2 combined with interferon-alpha and 5-fluorouracil in patients with metastatic renal cell cancer. 1994 Summer 2
88 7847809 Differential effects of recombinant interferon-alpha and 5-fluorouracil against colon cancer cells or against peripheral blood mononuclear cells. 1994 Sep-Oct 4
89 7923102 Anti-proliferative activity of interferon-alpha on human squamous carcinoma of tongue cell lines. 1994 Sep 30 1
90 7947102 The effect of 5-fluorouracil and alpha interferon and 5-fluorouracil and leucovorin on cellular anti-tumour immune responses in patients with advanced colorectal cancer. 1994 Nov 4
91 8026229 5-Fluorouracil-interferon-alpha 2b adjuvant treatment of Dukes C colorectal cancer. 1994 Jul 3
92 8074466 Recombinant human interferon alpha-2a increases 5-fluorouracil efficacy by elevating fluorouridine concentration in tumor tissue. 1994 May-Jun 2
93 8137250 Potentiation of the antitumor activity of 5-fluorouracil in colon carcinoma cells by the combination of interferon and deoxyribonucleosides results from complementary effects on thymidine phosphorylase. 1994 Mar 15 7
94 8186172 Interferon-alpha, 5-FU and prednisone in metastatic renal cell carcinoma: a phase II study. 1994 Mar 3
95 8192103 Double 5-fluorouracil modulation with folinic acid and recombinant alpha-2B-interferon. A phase I-II study in metastatic colorectal cancer patients. 1994 Jun 2
96 8221681 Cytokinetic effects of interferon in colorectal cancer tumors: implications in the design of the interferon/5-fluorouracil combinations. 1993 Nov 15 3
97 8239524 Hematotoxicity of 5-fluorouracil and alpha-interferon on the human normal hemopoietic progenitors. 1993 Sep-Oct 1
98 8246910 N-(phosphonacetyl)-L-aspartate synergistically enhances the cytotoxicity of 5-fluorouracil/interferon-alpha-2a against human colon cancer cell lines. 1993 Nov 2
99 8292812 A phase II study of 5-fluorouracil, leucovorin and interferon-alpha in advanced pancreatic cancer. 1993 Oct 2
100 8336197 Phase I trial of low-dose, prolonged continuous infusion fluorouracil plus interferon-alfa: evidence for enhanced fluorouracil toxicity without pharmacokinetic perturbation. 1993 Aug 3