2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

insulin-like growth factor 1 ; Rattus norvegicus







36 Article(s)
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1 34632857 Insulin-like growth factor reduced against decabromodiphenyl ether-209-induced neurodevelopmental toxicity in vivo and in vitro. 2021 Dec 2
2 25136768 Insulin-like growth factor-1 attenuates apoptosis and protects neurochemical phenotypes of dorsal root ganglion neurons with paclitaxel-induced neurotoxicity in vitro. 2017 Feb 1
3 27511131 Insulin-like growth factor 1 rescues R28 retinal neurons from apoptotic death through ERK-mediated BimEL phosphorylation independent of Akt. 2016 Oct 1
4 24995704 Involvement of two distinct signalling pathways in IGF-1-mediated central control of hypotensive effects in normotensive and hypertensive rats. 2014 Sep 1
5 23447091 CREB participates in the IGF-I-stimulation cyclin D1 transcription. 2013 Aug 1
6 22490886 Insulin-like growth factor-1 induces the phosphorylation of PRAS40 via the PI3K/Akt signaling pathway in PC12 cells. 2012 May 10 1
7 22537549 Cardiac fibroblast death by ischemia/reperfusion is partially inhibited by IGF-1 through both PI3K/Akt and MEK-ERK pathways. 2012 Aug 1
8 20821260 IGF-1 reduces BACE-1 expression in PC12 cells via activation of PI3-K/Akt and MAPK/ERK1/2 signaling pathways. 2011 Jan 1
9 21092510 [Insulin-like growth factor 1 regulates expression of stem cell factor through ERKMAPK signaling pathway in gastric smooth muscle cell]. 2010 Sep 14 1
10 18595745 IGF-1 regulation of type II collagen and MMP-13 expression in rat endplate chondrocytes via distinct signaling pathways. 2009 Jan 2
11 18076874 Effects of tanshinone VI on phosphorylation of ERK and Akt in isolated cardiomyocytes and cardiac fibroblasts. 2008 Feb 12 1
12 18278798 PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease. 2008 Apr 1
13 18453753 IGF-1 protects against dexamethasone-induced cell death in insulin secreting INS-1 cells independent of AKT/PKB phosphorylation. 2008 1
14 17335809 Effects of insulin-like growth factor 1 on synaptic excitability in cultured rat hippocampal neurons. 2007 May 1
15 17365107 Involvement of p42/44 MAPK in the effects of ethanol on secretion of insulin-like growth factor (IGF)-I and insulin-like growth factor binding protein (IGFBP)-1 in primary cultured rat hepatocytes. 2007 Feb 1
16 16586540 Effects of betaine on ethanol-stimulated secretion of IGF-I and IGFBP-1 in rat primary hepatocytes: involvement of p42/44 MAPK activation. 2006 Mar 21 1
17 15845624 Insulin-like growth factor (IGF)-I stimulates cell proliferation and induces IGF binding protein (IGFBP)-3 and IGFBP-5 gene expression in cultured growth plate chondrocytes via distinct signaling pathways. 2005 Jul 2
18 16342423 PKC alpha-dependent regulation of the IGF1 receptor in adult and embryonic rat cardiomyocytes. 2005 Jul 2
19 12959952 Inhibition of MAP/ERK kinase prevents IGF-I-induced hypertrophy in rat muscles. 2004 Jan 3
20 14765977 FSH activates phosphatidylinositol 3-kinase/protein kinase B signaling pathway in 20-day-old Sertoli cells independently of IGF-I. 2004 Feb 3
21 15068962 IGF-I increases IGFBP-5 and collagen alpha1(I) mRNAs by the MAPK pathway in rat intestinal smooth muscle cells. 2004 May 1
22 15151916 Dual effect of insulin-like growth factor on the apical 70-pS K channel in the thick ascending limb of rat kidney. 2004 Jun 1
23 12239091 Activation of phosphatidylinositol 3-kinase contributes to insulin-like growth factor I-mediated inhibition of pancreatic beta-cell death. 2002 Oct 1
24 11228094 Insulin-like growth factor-1 protects H9c2 cardiac myoblasts from oxidative stress-induced apoptosis via phosphatidylinositol 3-kinase and extracellular signal-regulated kinase pathways. 2001 Jan 26 1
25 11548882 Role of calcineurin in insulin-like growth factor-1-induced hypertrophy of cultured adult rat ventricular myocytes. 2001 Sep 1
26 11683530 Stimulatory effect of zinc on deoxyribonucleic acid synthesis in bone growth of newborn rats: enhancement with zinc and insulin-like growth factor-I. 2001 Sep 2
27 10788447 Stimulation of protein kinase C modulates insulin-like growth factor-1-induced akt activation in PC12 cells. 2000 May 5 1
28 10816436 Signalling pathways of insulin-like growth factor-I that are augmented by cAMP in FRTL-5 cells. 2000 Jun 1 2
29 10873673 Extracellular regulated kinase, but not protein kinase C, is an antiapoptotic signal of insulin-like growth factor-1 on cultured cardiac myocytes. 2000 Jul 5 1
30 11027947 The role of the cyclic GMP-inhibited cyclic AMP-specific phosphodiesterase (PDE3) in regulating clonal BRIN-BD11 insulin secreting cell survival. 2000 Aug 1
31 11256230 Insulin-like growth factor I inhibits cardiomyocyte apoptosis and the underlying signal transduction pathways. 2000 Oct 1
32 9915817 Insulin-like growth factor I-mediated activation of the transcription factor cAMP response element-binding protein in PC12 cells. Involvement of p38 mitogen-activated protein kinase-mediated pathway. 1999 Jan 29 1
33 9927318 Insulin-like growth factor I suppresses parathyroid hormone (PTH)/PTH-related protein receptor expression via a mitogen-activated protein kinase pathway in UMR-106 osteoblast-like cells. 1999 Feb 1
34 10579338 Insulin-like growth factor signaling pathways in rat hepatic stellate cells: importance for deoxyribonucleic acid synthesis and hepatocyte growth factor production. 1999 Dec 2
35 9490004 Effect of inhibitors of signal transduction on IGF-1-induced protein synthesis associated with hypertrophy in cultured neonatal rat ventricular myocytes. 1998 Jan 30 1
36 8995241 Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways. 1997 Jan 3 1