Title : IGF-1 regulation of type II collagen and MMP-13 expression in rat endplate chondrocytes via distinct signaling pathways.

Pub. Date : 2009 Jan

PMID : 18595745






2 Functional Relationships(s)
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1 In contrast, the ERK/MAPK inhibitor PD98059 significantly inhibited the effect of IGF-1 on MMP-13 mRNA repression and enhanced IGF-1-induced Col2a1 mRNA expression. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one insulin-like growth factor 1 Rattus norvegicus
2 In contrast, the ERK/MAPK inhibitor PD98059 significantly inhibited the effect of IGF-1 on MMP-13 mRNA repression and enhanced IGF-1-induced Col2a1 mRNA expression. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one insulin-like growth factor 1 Rattus norvegicus