Title : Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5'-deoxy-5-fluorouridine.

Pub. Date : 1993

PMID : 8339382






1 Functional Relationships(s)
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1 The increased susceptibility would be a result of the induction of thymidine phosphorylase (TdR Pase), which is the essential enzyme for the conversion of 5"-dFUrd to 5-FUra. Fluorouracil thymidine phosphorylase Homo sapiens